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Therapy of hypertension in elderly population and its potential risks

Jiří Widimský

    Vnitrni Lekarstvi
    |November 19, 2022
    PubMed

    Insights

    Arterial hypertension is common in older adults, often presenting as systolic/diastolic or isolated systolic hypertension. Careful antihypertensive therapy is beneficial, reducing cardiovascular events and mortality in the elderly.

    Area of Science:

    • Gerontology
    • Cardiology
    • Pharmacology

    Background:

    • Arterial hypertension is a prevalent condition in individuals aged 65 and older.
    • Hypertension in the elderly commonly manifests as systolic/diastolic or isolated systolic hypertension.

    Purpose of the Study:

    • To summarize the fundamental therapeutic principles for managing hypertension in elderly subjects.
    • To discuss potential complications and considerations specific to older, frail individuals.

    Main Methods:

    • Review of basic therapeutic principles for hypertension in the elderly.
    • Discussion of slow and careful uptitration of antihypertensive therapy.
    • Analysis of potential complications and caveats in this demographic.

    Main Results:

    • Pharmacotherapy for hypertension in the elderly is overwhelmingly beneficial.
    • Treatment leads to a significant decrease in cardiovascular (CV) events.
    • Treatment also reduces overall CV mortality.

    Conclusions:

    • Gradual and cautious adjustment of antihypertensive medications is crucial for elderly patients.
    • Careful management can mitigate risks and complications in frail older adults.
    • Effective pharmacotherapy significantly improves cardiovascular outcomes and survival in hypertensive elderly individuals.

    Keywords:
    arterial hypertensionbenefitelderlyrisktherapytype 2 diabetes

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