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TDD-UNet:Transformer with double decoder UNet for COVID-19 lesions segmentation
Xuping Huang1, Junxi Chen2, Mingzhi Chen3
1Computer School, University of South China, Hengyang 421001, China.
Computers in Biology and Medicine
|November 20, 2022
Summary
A new Transformer-based UNet model (TDD-UNet) enhances COVID-19 lesion segmentation by integrating multi-head self-attention for global context and a dual decoder for improved detail accuracy in medical imaging.
Area of Science:
- Medical Image Analysis
- Artificial Intelligence in Healthcare
- Radiology
Background:
- The COVID-19 pandemic poses significant global health risks.
- Accurate segmentation of COVID-19 lesions in medical images is crucial for diagnosis and treatment.
- Traditional UNet models struggle with long-range dependencies in images, limiting segmentation accuracy.
Purpose of the Study:
- To develop an advanced segmentation model for COVID-19 lesions.
- To address the limitations of existing UNet and Transformer models in capturing both global context and fine-grained details.
Main Methods:
- Proposed TDD-UNet, a novel architecture combining Transformer's multi-head self-attention with a dual decoder UNet.
- Integrated Transformer Encoder into the UNet encoding layer for global context extraction.
- Employed a dual decoder structure with background prediction and deep supervision for enhanced foreground segmentation.
Main Results:
- TDD-UNet demonstrated superior performance in segmenting COVID-19 lesions across CT and CXR modalities.
- Achieved higher Dice and Jaccard scores with lower standard deviation compared to existing methods.
- Ablation studies confirmed the effectiveness of key components in the TDD-UNet model.
Conclusions:
- The proposed TDD-UNet model offers improved accuracy and robustness for COVID-19 lesion segmentation.
- This approach effectively combines global context and local details for precise medical image segmentation.
- TDD-UNet shows significant potential for clinical application in COVID-19 diagnosis.

