Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Theories of Dissolution: The Danckwerts' Model and Interfacial Barrier Model01:09

Theories of Dissolution: The Danckwerts' Model and Interfacial Barrier Model

390
Various dissolution theories provide insight into the factors that influence the dissolution rate. Danckwerts' Model suggests that turbulence, rather than a stagnant layer, characterizes the dissolution medium at the solid-liquid interface. In this model, the agitated solvent contains macroscopic packets that move to the interface via eddy currents, facilitating the absorption and delivery of the drug to the bulk solution. The regular replenishment of solvent packets maintains the...
390
Colloids03:22

Colloids

17.8K
Children at play often make suspensions such as mixtures of mud and water, flour and water, or a suspension of solid pigments in water known as tempera paint. These suspensions are heterogeneous mixtures composed of relatively large particles that are visible to the naked eye or can be seen with a magnifying glass. They are cloudy, and the suspended particles settle out after mixing. On the other hand, a solution is a homogeneous mixture in which no settling occurs and in which the dissolved...
17.8K
Intermolecular Forces and Physical Properties02:56

Intermolecular Forces and Physical Properties

21.3K
21.3K
Intermolecular Forces03:13

Intermolecular Forces

59.0K
Atoms and molecules interact through bonds (or forces): intramolecular and intermolecular. The forces are electrostatic as they arise from interactions (attractive or repulsive) between charged species (permanent, partial, or temporary charges) and exist with varying strengths between ions, polar, nonpolar, and neutral molecules. The different types of intermolecular forces are ion–dipole, dipole–dipole, hydrogen bonds, and dispersion; among these, dipole–dipole, hydrogen...
59.0K
Comparing Intermolecular Forces: Melting Point, Boiling Point, and Miscibility02:34

Comparing Intermolecular Forces: Melting Point, Boiling Point, and Miscibility

44.9K
Intermolecular forces are attractive forces that exist between molecules. They dictate several bulk properties, such as melting points, boiling points, and solubilities (miscibilities) of substances. Molar mass, molecular shape, and polarity affect the strength of different intermolecular forces, which influence the magnitude of physical properties across a family of molecules.
Temporary attractive forces like dispersion are present in all molecules, whether they are polar or nonpolar. They...
44.9K
Colloidal precipitates01:09

Colloidal precipitates

719
The high insolubility of some precipitates can result in an unfavorable relative supersaturation. This can lead to colloidal particles with a large surface-to-mass ratio, where adsorption is promoted. For instance, in the precipitation of silver chloride, silver ions are adsorbed on the surface of the colloidal particles, forming a primary layer. This layer attracts ions of opposite charge (such as nitrate ions), forming a diffuse secondary layer of adsorbed ions. This electric double layer...
719

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Linking Local Water Electrostatic Potentials to Measured Hydrogen Evolution Onset in Aqueous Electrolytes.

The journal of physical chemistry letters·2026
Same author

Molecular origins of capillary wave structure and interfacial viscosity at surfactant-laden oil-water interfaces.

The Journal of chemical physics·2026
Same author

Magnesium-Assisted Photoinduced Polarity-Mismatched Coupling: Access to Thioester-Decorated Oxindoles and Fused Heterocycles.

ChemSusChem·2026
Same author

Uranium Chelation by Pyrazine-2-amidoxime: Speciation, Decorporation, and Computational Studies.

Inorganic chemistry·2026
Same author

Accurate and Efficient Prediction of p<i>K</i><sub>w</sub> in Aqueous Electrolytes Using Local Electrostatic Potentials.

The journal of physical chemistry letters·2025
Same author

Electron Density Transport During Chemical Reactions.

Journal of chemical theory and computation·2025

Related Experiment Video

Updated: Aug 20, 2025

Controlling the Size, Shape and Stability of Supramolecular Polymers in Water
16:24

Controlling the Size, Shape and Stability of Supramolecular Polymers in Water

Published on: August 2, 2012

18.7K

Modulating Aggregation in Microemulsions: The Dispersion by Competitive Intermolecular Interaction Model.

Biswajit Sadhu1, Aurora E Clark2,3,4

  • 1Health Physics Division, Bhabha Atomic Research Centre, Trombay, Mumbai, Maharashtra400085, India.

The Journal of Physical Chemistry Letters
|November 21, 2022
PubMed
Summary
This summary is machine-generated.

A new model explains how phase modifiers control aggregation in emulsions. Strong hydrogen bonding by phase modifiers disrupts micellar cores, reducing aggregate size and improving solution uniformity.

More Related Videos

Self-Nanoemulsification of Healthy Oils to Enhance the Solubility of Lipophilic Drugs
08:18

Self-Nanoemulsification of Healthy Oils to Enhance the Solubility of Lipophilic Drugs

Published on: July 27, 2022

1.2K
Synthesis of Monocyte-targeting Peptide Amphiphile Micelles for Imaging of Atherosclerosis
08:01

Synthesis of Monocyte-targeting Peptide Amphiphile Micelles for Imaging of Atherosclerosis

Published on: November 17, 2017

7.4K

Related Experiment Videos

Last Updated: Aug 20, 2025

Controlling the Size, Shape and Stability of Supramolecular Polymers in Water
16:24

Controlling the Size, Shape and Stability of Supramolecular Polymers in Water

Published on: August 2, 2012

18.7K
Self-Nanoemulsification of Healthy Oils to Enhance the Solubility of Lipophilic Drugs
08:18

Self-Nanoemulsification of Healthy Oils to Enhance the Solubility of Lipophilic Drugs

Published on: July 27, 2022

1.2K
Synthesis of Monocyte-targeting Peptide Amphiphile Micelles for Imaging of Atherosclerosis
08:01

Synthesis of Monocyte-targeting Peptide Amphiphile Micelles for Imaging of Atherosclerosis

Published on: November 17, 2017

7.4K

Area of Science:

  • Physical Chemistry
  • Colloid Science
  • Materials Science

Background:

  • Aggregation phenomena in water-in-oil emulsions are influenced by additives.
  • Existing models for amphiphile distribution (cosolvent, cosurfactant) lack detailed mechanistic insight.
  • Understanding intermolecular interactions is key to controlling emulsion properties.

Purpose of the Study:

  • To develop a phenomenological model for phase modifier action in emulsions.
  • To elucidate the role of intermolecular interactions in controlling aggregation.
  • To introduce and define the "polar disruption regime".

Main Methods:

  • Development of the "Dispersion by Competitive Intermolecular Interaction" (DCI) model.
  • Re-examination of existing cosolvent and cosurfactant association models.
  • Application of the DCI model to a specific system: N,N,N',N'-tetraoctyl diglycolamide with phase modifiers.

Main Results:

  • The DCI model explicitly links intermolecular interaction strength to aggregate size and phase behavior.
  • Distinct regimes within the DCI model explain diverse amphiphile behaviors.
  • The "polar disruption regime" was identified, characterized by phase modifier disruption of micellar cores.

Conclusions:

  • The DCI model provides a framework for understanding phase modifier mechanisms.
  • Phase modifiers can significantly alter aggregate structure and emulsion properties.
  • Hydrogen bonding interactions play a critical role in the observed "polar disruption regime".