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Updated: Aug 20, 2025

Surgical Treatment of an Endolymphatic Sac Tumor
Published on: May 26, 2023
[Neuroendocrine adenoma middle ear]
A I Kryukov1,2, E V Garov1,2, V N Zelenkova1
1L.I. Sverzhevskiy Research Institute of Clinical Otorhinolaryngology, Moscow, Russia.
Abstract:
Neuroendocrine adenoma (NEA) is an extremely rare pathology and accounts for less than 2% of all ear tumors. The article provides an overview of the diagnosis, classification, treatment methods and algorithm for monitoring patients with NEA of the middle ear. 6 cases of NEA of the tympanic cavity are described in detail, which were diagnosed and treated in GBUZ NIKIO named after N.N. L.I. Sverzhevsky DZM for the last 5 years. Diagnosis of NEA of the middle ear is possible when performing high-resolution multislice computed tomography of the temporal bones and magnetic resonance imaging with contrast enhancement, however, the neoplasm can be verified only after a histological examination with the determination of the immunophenotype. Differential diagnosis of NEA of the tympanic cavity with other processes of the middle ear must be carried out at each stage of the diagnostic path. Surgical treatment, depending on the volume of education, allows you to remove it completely and improve the auditory function.

