Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Multiple Sclerosis l: Introduction01:19

Multiple Sclerosis l: Introduction

Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Do cognitive dysfunction and fatigue impact illness perception in people living with multiple sclerosis?

Arquivos de neuro-psiquiatria·2026
Same author

Active tuberculosis and multiple sclerosis: the importance of screening before treatment.

Arquivos de neuro-psiquiatria·2025
Same author

The impact of changing diagnostic criteria on disability in a Brazilian multiple sclerosis cohort.

Arquivos de neuro-psiquiatria·2025
Same author

Teaching NeuroImage: Schistosomiasis Involving the Conus Medullaris.

Neurology·2024
Same author

Standard and Extend High-Frequency Audiometry in Sudden Sensorineural Hearing Loss: Impacts on Tinnitus and Mental Health.

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·2024
Same author

Spontaneous intracranial hypotension: from cerebral venous thrombosis to neurosurgical treatment: a case series experience from a Brazilian tertiary health care center.

Arquivos de neuro-psiquiatria·2023

Related Experiment Video

Updated: Jun 18, 2026

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
11:35

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

58.1K

Postural Control in Relapsing-Remitting Multiple Sclerosis.

Flavia Salvaterra Cusin1, Andreza Tomaz1, Maurício Malavasi Ganança1

  • 1Department of Otolaryngology and Head and Neck Surgery, Otology and Neurotology Division, Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.

International Archives of Otorhinolaryngology
|November 21, 2022
PubMed
Summary

Relapsing-remitting multiple sclerosis (RRMS) patients exhibit significant postural instability and increased fall risk, linked to sensory system deficits and self-perceived dizziness. These findings highlight the impact of RRMS on balance and quality of life.

Keywords:
dizzinessmultiple sclerosispostural balancequality of liferelapsing-remitting

More Related Videos

Experimental Methods to Study Human Postural Control
08:12

Experimental Methods to Study Human Postural Control

Published on: September 11, 2019

9.6K
Evaluating Postural Control and Lower-extremity Muscle Activation in Individuals with Chronic Ankle Instability
07:52

Evaluating Postural Control and Lower-extremity Muscle Activation in Individuals with Chronic Ankle Instability

Published on: September 18, 2020

8.5K

Related Experiment Videos

Last Updated: Jun 18, 2026

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
11:35

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

58.1K
Experimental Methods to Study Human Postural Control
08:12

Experimental Methods to Study Human Postural Control

Published on: September 11, 2019

9.6K
Evaluating Postural Control and Lower-extremity Muscle Activation in Individuals with Chronic Ankle Instability
07:52

Evaluating Postural Control and Lower-extremity Muscle Activation in Individuals with Chronic Ankle Instability

Published on: September 18, 2020

8.5K

Area of Science:

  • Neurology
  • Rehabilitation Medicine
  • Biomedical Engineering

Background:

  • Postural instability is a primary disabling symptom in relapsing-remitting multiple sclerosis (RRMS).
  • Understanding the specific nature of postural control deficits is crucial for effective management.

Purpose of the Study:

  • To comprehensively evaluate postural control in individuals with RRMS.
  • To identify correlations between postural instability, functional disability, and subjective dizziness perception.

Main Methods:

  • A study involving 79 participants (51 RRMS patients, 28 healthy controls) aged 18-65.
  • Evaluations included anamnesis, Dizziness Handicap Inventory (DHI), visual vertigo analog scale (VVAS), and static posturography (Tetrax IBS).

Main Results:

  • RRMS patients showed mild DHI and VVAS scores but significant differences in posturography indices compared to controls.
  • Peripheral vestibular, visual, and/or somatosensory dysfunctions were prevalent (51.0%).
  • Higher disability scores and DHI/VVAS scores correlated with increased fall risk.

Conclusions:

  • RRMS patients experience postural control impairment due to general instability and sensory system deficiencies.
  • Fall risk is associated with the severity of functional disability and the impact of dizziness on quality of life.
  • Targeted interventions addressing sensory integration and dizziness are needed for RRMS management.