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Comorbidities, Associated Diseases, and Risk Assessment in COVID-19-A Systematic Review
Andreea Fitero1, Simona Gabriela Bungau1,2, Delia Mirela Tit1,2
1Doctoral School of Biomedical Sciences, Faculty of Medicine and Pharmacy, University of Oradea, Oradea 410073, Romania.
Insights
The COVID-19 pandemic increased deaths, particularly in patients with comorbidities. Prioritizing risk identification and resource allocation is crucial for overwhelmed health systems managing severe cases.
Area of Science:
- Public Health
- Epidemiology
- Infectious Diseases
Background:
- The COVID-19 pandemic has led to increased mortality, especially in individuals with pre-existing health conditions (comorbidities).
- Healthcare systems face immense pressure due to high patient volumes, limited resources, and the severity of COVID-19 cases.
- Comorbidities such as diabetes, cardiovascular disease, obesity, chronic lung disease, and neurodegenerative disorders significantly elevate the risk of mortality and hospitalization from SARS-CoV-2 infection.
Approach:
- This study emphasizes the critical need for proactive strategies in managing the impact of the COVID-19 pandemic.
- Focus is placed on identifying high-risk patients early to mitigate severe outcomes.
- The approach advocates for risk stratification and equitable resource allocation to support healthcare systems.
Key Points:
- Comorbidities are strongly associated with increased COVID-19 mortality and hospitalization rates.
- Healthcare infrastructure is strained by the pandemic's demands and resource limitations.
- Early identification and risk-based stratification of patients are essential for effective pandemic response.
Conclusions:
- Prioritizing the rapid identification and risk stratification of patients with COVID-19 is paramount for global health systems.
- Effective allocation of human, financial, and logistical resources based on risk assessment is necessary.
- Addressing the disproportionate impact of COVID-19 on vulnerable populations with comorbidities must be a global health priority.
Abstract:
It is considered that COVID-19's pandemic expansion is responsible for the particular increase in deaths, especially among the population with comorbidities. The health system is often overwhelmed by the large number of cases of patients addressing it, by the regional limitation of funds, and by the gravity of cases at subjects suffering from this pathology. Several associated conditions including diabetes, cardiovascular illnesses, obesity, persistent lung condition, neurodegenerative diseases, etc., increase the mortality risk and hospitalization of subjects suffering from COVID-19. The rapid identification of patients with increased risk of death from the SARS-CoV-2 virus, the stratification in accordance with the risk and the allocation of human, financial, and logistical resources in proportion must be a priority for health systems worldwide.
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