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High-throughput Synthesis of Carbohydrates and Functionalization of Polyanhydride Nanoparticles

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Microbial Polysaccharide-Based Nanoformulations for Nutraceutical Delivery.

Nandita Srivastava^1,2, Anirban Roy Choudhury¹

¹Biochemical Engineering Research & Process Development Centre (BERPDC), Institute of Microbial Technology (IMTECH), Council of Scientific and Industrial Research (CSIR), Sector 39A, Chandigarh 160036, India.

|November 21, 2022

Summary

Microbial polysaccharides offer a novel solution for enhancing nutraceutical delivery. These biocompatible nanocarriers improve the stability and bioavailability of bioactive compounds, addressing limitations of traditional plant-derived nutraceuticals.

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Area of Science:

Food Science and Technology
Nanotechnology
Nutraceuticals

Background:

Growing health consciousness and sedentary lifestyles increase demand for preventive healthcare and nutraceuticals.
Plant-derived nutraceuticals face challenges like instability, poor solubility, and reduced bioavailability.
Synthetic drugs present high costs and long-term adverse effects, driving interest in natural alternatives.

Purpose of the Study:

To comprehensively review microbial polysaccharides-based nanodelivery systems for nutraceuticals.
To explore the techno-commercial aspects of these nanotechnological preparations.
To identify future research perspectives in microbial polysaccharide nanoformulations.

Main Methods:

Review of existing literature on microbial polysaccharides and nanoencapsulation technologies.
Analysis of the properties of microbial polysaccharides as nanocarriers.
Discussion of the advantages of microbial polysaccharide nanoformulations over conventional systems.

Main Results:

Microbial polysaccharides are biocompatible, non-toxic, non-immunogenic, and US-FDA approved, making them suitable for food-grade applications.
Nanoencapsulation using microbial polysaccharides enhances the stability, solubility, and bioavailability of labile nutraceutical compounds.
These nanoformulations can be integrated into functional foods and beverages without negatively impacting sensory properties.

Conclusions:

Microbial polysaccharide-based nanodelivery systems represent a promising frontier for improving nutraceutical efficacy and application.
These systems offer a sustainable and effective alternative to overcome the limitations of traditional nutraceutical formulations.
Further research into techno-commercial aspects and applications is warranted to fully realize the potential of these nanotechnologies.