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Future opportunities for the Athlete Biological Passport
Bastien Krumm1, Francesco Botrè1,2, Jonas J Saugy1
1Research and Expertise in Anti-Doping Sciences, Institute of Sport Sciences, University of Lausanne, Lausanne, Switzerland.
Frontiers in Sports and Active Living
|November 21, 2022
Summary
The Athlete Biological Passport (ABP) uses indirect monitoring to detect doping. Innovations in biomarkers and AI aim to improve its accuracy despite confounding factors.
Area of Science:
- Sports Science
- Anti-Doping Research
- Biomarker Development
Background:
- The Athlete Biological Passport (ABP) indirectly detects doping by monitoring biological markers.
- Current ABP methods using urine and blood face challenges from genetic and environmental factors.
- There is a need for more sensitive and specific biomarkers to enhance anti-doping efforts.
Purpose of the Study:
- To highlight promising innovations in the Athlete Biological Passport (ABP).
- To explore new strategies for improving longitudinal monitoring in sports.
- To discuss the integration of advanced technologies like omics and AI in anti-doping.
Main Methods:
- Review of current and emerging strategies for ABP enhancement.
- Exploration of omics strategies for biomarker discovery.
- Investigation of artificial intelligence (AI) and machine learning for data interpretation.
Main Results:
- Development of new, more specific biomarkers is crucial.
- Addressing confounding factors is essential for accurate ABP interpretation.
- Machine learning approaches show promise for expert analysis of biological profiles.
Conclusions:
- Innovations in biomarkers and AI are vital for advancing the ABP.
- Continued research is needed to overcome variability and confounding factors.
- Integrating advanced analytical techniques will strengthen anti-doping measures in sports.
