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Elizabethkingia meningoseptica Infection in COVID-19 Patients

Mas Chaponda1, Adila Shaukat1, Mohammad Wajeh Dulli2

  • 1Infectious Diseases Department, Hamad Medical Corporation, Doha, QAT.

Cureus
|November 21, 2022
PubMed

Insights

Coinfections with Elizabethkingia meningoseptica (EM) are emerging in severe COVID-19 patients. These superinfections show high antimicrobial resistance, leading to poor patient outcomes.

Area of Science:

  • Infectious Diseases
  • Critical Care Medicine
  • Microbiology

Background:

  • The COVID-19 pandemic has seen an increase in bacterial and fungal coinfections.
  • Antimicrobial resistance is a growing concern in managing severe COVID-19 cases.

Observation:

  • Three cases of Elizabethkingia meningoseptica (EM) superinfections in COVID-19 patients are presented.
  • These patients were critically ill, intubated, and had central venous catheters.
  • They received extensive prior treatment including antibiotics, antivirals, and dexamethasone.

Findings:

  • Elizabethkingia meningoseptica isolates demonstrated resistance to most tested antibiotics.
  • All three patients experienced poor treatment outcomes.

Implications:

  • This highlights the need for vigilance regarding unusual bacterial superinfections in severe COVID-19.
  • Emergence of multidrug-resistant EM poses a significant challenge in critical care settings.
  • Further research into optimal management strategies for EM superinfections in immunocompromised patients is warranted.
Keywords:
antibiotic resistancebacteremiacovid-19elizabethkingia meningosepticahealthcare associated infectionspolymicrobial bacteremiaprognosis

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