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Updated: Aug 20, 2025

In Vitro Thrombosis Test for Ventricular Assist Devices
Published on: March 21, 2025
Mechanical Aortic Valve Thrombosis Successfully Treated With Intravenous Thrombolytic Therapy: A Case Report
Shobha Mandal1, Dipesh K Rohita2, Sanjay Paudel1
1Internal Medicine, Guthrie Robert Packer Hospital, Sayre, USA.
Abstract:
Mechanical prosthetic valves, like all foreign bodies, are thrombogenic, requiring anticoagulation to avoid thrombosis and reduce the risk of catastrophic stroke. We reported a case of a 42-year-old female that developed mechanical valve thrombosis and was successfully treated with low infusion thrombolytic therapy using alteplase (tPA, tissue plasminogen activator).
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