Central laboratory and point-of-care cardiac marker testing capacity of tertiary hospitals in Nigeria - a multicenter

Ijeoma Angela Meka1, Ochuko Otokunefor2, Asuquo Ene3

  • 1University of Nigeria Faculty of Medical Sciences, Chemical Pathology.

African Health Sciences
|November 21, 2022
PubMed

Insights

Cardiac marker testing capacity in Nigerian tertiary hospitals is insufficient. Only 55.88% of hospitals have functional facilities, highlighting a critical need for improvement in diagnosing cardiovascular diseases like Acute Coronary Syndrome (ACS).

Area of Science:

  • Clinical Diagnostics
  • Cardiovascular Medicine
  • Healthcare Management

Background:

  • Cardiovascular diseases (CVDs) are leading causes of illness and death globally.
  • Cardiac marker testing is crucial for diagnosing Acute Coronary Syndrome (ACS).
  • Tertiary hospitals, particularly teaching hospitals, are expected to provide advanced cardiac diagnostics.

Purpose of the Study:

  • To assess the availability and functionality of central laboratory and point-of-care cardiac marker testing services.
  • To determine the cardiac marker testing capacity in Nigerian tertiary hospitals.
  • To identify barriers to establishing comprehensive cardiac marker testing services.

Main Methods:

  • A cross-sectional survey was conducted among government-owned tertiary hospitals in Nigeria.
  • Data were collected using semi-structured, self-administered questionnaires.
  • Statistical analysis was performed using Stata version 13.

Main Results:

  • Out of 34 participating hospitals, only 19 (55.88%) possessed functional cardiac marker testing facilities (point-of-care, central laboratory, or both).
  • The primary reason for lacking facilities was the inability to fund equipment procurement.
  • In hospitals with testing capabilities, central laboratories predominantly housed the testing devices.

Conclusions:

  • The capacity for cardiac marker testing in Nigerian tertiary hospitals is currently inadequate for both point-of-care and central laboratory services.
  • Significant improvements are required to enhance diagnostic capabilities for patients requiring cardiac marker evaluation.
  • Addressing funding gaps for equipment is essential to expand testing services.
Abstract

Related Concept Videos

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
139
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
20
Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
232
Cardiac Catheterization IV: Nursing Management01:26

Cardiac Catheterization IV: Nursing Management

Nursing responsibilities before cardiac catheterization include:Assess for allergies and establish baseline health status.Before cardiac catheterization, assess the patient for allergies to contrast dye. Perform a comprehensive baseline assessment, including vital signs, heart and breath sounds, and a neurovascular assessment of the extremities, noting distal pulses, skin color, and temperature. Instruct the patient to fast for 8-12 hours before the procedure. Evaluate baseline laboratory...
119
Cardiac Catheterization II: Right Heart Catheterization01:21

Cardiac Catheterization II: Right Heart Catheterization

Right Heart Catheterization: An OverviewRight heart catheterization is an invasive diagnostic procedure that measures right-sided cardiac and pulmonary artery pressures, calculates cardiac output, and identifies intracardiac shunts. It provides detailed hemodynamic data essential for diagnosing and managing various cardiovascular conditions, such as pulmonary hypertension.Access SitesCommon access sites for right heart catheterization include the internal jugular vein in the neck region, the...
79
Cardiac Catheterization I: Pre-Procedure Overview01:28

Cardiac Catheterization I: Pre-Procedure Overview

Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
121