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Relationship between acupuncture and transient receptor potential vanilloid: Current and future directions
Dan Luo1,2, Li Liu3, Hai-Ming Zhang1,4
1Department of Acupuncture and Moxibustion, Hubei University of Traditional Chinese Medicine, Wuhan, China.
Frontiers in Molecular Neuroscience
|November 21, 2022
Summary
Acupuncture
Area of Science:
- Neuroscience
- Complementary and Alternative Medicine
Background:
- Acupuncture is a widely used therapy, but its mechanisms are not fully understood.
- Transient receptor potential vanilloid (TRPV) channels are increasingly implicated in acupuncture's effects.
Purpose of the Study:
- To explore the relationship between acupuncture and TRPV channels.
- To elucidate the multi-targeted and biphasic regulation of TRPV channels by acupuncture.
Main Methods:
- Review of existing studies on acupuncture and TRPV channels.
- Analysis of TRPV channel modulation in the central and peripheral nervous systems.
- Investigation of TRPV channel expression and function at acupoints.
Main Results:
- Acupuncture modulates TRPV1 and TRPV4 channels in the autonomic nervous system (ANS).
- TRPV1 and TRPV4 expression and function are specific to acupuncture at acupoints.
- Modulation of TRPV channels at different anatomical levels impacts acupuncture's therapeutic efficacy.
Conclusions:
- TRPV channels offer insights into acupuncture's underlying principles.
- Acupuncture may serve as a therapeutic approach for TRPV channel-related conditions.
Keywords:
TRPV channelsacupunctureautonomic nervous systemcentral nervous systemperipheral sensory nervousMore Related Videos
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