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Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
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Adult Intussusception in Chronic Marijuana Users.

Jiten P Kothadia1,2, Anwesh Dash3, Rajanshu Verma3

  • 1James D. Eason Transplant Institute, Methodist University Hospital, Memphis, TN, USA.

Gastroenterology Research
|November 21, 2022
PubMed
Summary
This summary is machine-generated.

Adult intussusception (AI) is rare, often caused by malignancy. This study explores marijuana use as a potential cause for AI in chronic users, highlighting its gastrointestinal effects.

Keywords:
Abdominal painBowel obstructionChronic marijuana useIntussusception

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Area of Science:

  • Gastroenterology
  • Toxicology
  • Public Health

Background:

  • Intussusception is common in children but rare in adults.
  • Adult intussusception (AI) is frequently associated with a pathological lead point, often malignancy.
  • Intra-luminal irritants are considered in cases without a clear pathological lead point.

Observation:

  • Marijuana use has significantly increased in the United States.
  • Increased public acceptance and legalization of marijuana have led to more prominent adverse side effects.
  • Marijuana is known to disrupt gastrointestinal tract motility by inhibiting cholinergic mechanisms.

Findings:

  • Four cases of adult intussusception in chronic marijuana users are presented.
  • This review highlights the potential role of marijuana as an intra-luminal irritant causing AI.
  • The study emphasizes the adverse gastrointestinal effects of increasing marijuana use.

Implications:

  • Clinicians should consider marijuana use in the differential diagnosis of adult intussusception, especially in the absence of a pathological lead point.
  • Increased awareness of marijuana's gastrointestinal effects is crucial given its rising prevalence.
  • Further research into the mechanisms by which marijuana affects gut motility and potentially causes intussusception is warranted.