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Updated: Aug 20, 2025

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COVID-19 classification using chest X-ray images based on fusion-assisted deep Bayesian optimization and Grad-CAM

Ameer Hamza1, Muhammad Attique Khan1, Shui-Hua Wang2

  • 1Department of Computer Science, HITEC University, Taxila, Pakistan.

Frontiers in Public Health
|November 21, 2022
PubMed
Summary
This summary is machine-generated.

This study introduces an AI framework using Bayesian optimized deep convolutional neural networks (DCNNs) to accurately classify COVID-19 from chest X-rays, aiding in rapid diagnosis.

Keywords:
Bayesian optimizationcorona virusdeep learningfusionhyperparametersmulti-filters contrast enhancement

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Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Machine Learning

Background:

  • COVID-19 has severe global health and economic impacts.
  • Chest X-rays (CXRs) are vital for COVID-19 detection, but manual analysis is challenging.
  • Deep convolutional neural networks (DCNNs) show promise for automated medical image analysis.

Purpose of the Study:

  • To propose a Bayesian optimized DCNN and explainable AI framework for COVID-19 classification from CXRs.
  • To enhance the accuracy and efficiency of COVID-19 detection using automated image analysis.
  • To provide visual explanations for AI-driven diagnoses.

Main Methods:

  • A multi-filter contrast enhancement technique was applied to CXRs.
  • Two pre-trained DCNN models (EfficientNet-B0, MobileNet-V2) were fine-tuned and trained using Bayesian optimization (BO).
  • Features were extracted, fused using a slicing-based serial approach, and classified with machine learning classifiers. Grad-CAM was used for visualization.

Main Results:

  • The proposed framework achieved high accuracies of 98.8%, 97.9%, and 99.4% on three public COVID-19 datasets.
  • Bayesian optimization improved hyperparameter selection for DCNNs.
  • Grad-CAM effectively highlighted infected regions in CXRs.

Conclusions:

  • The developed AI framework demonstrates high efficacy in classifying COVID-19 from chest X-rays.
  • The integration of Bayesian optimization and explainable AI enhances diagnostic capabilities.
  • This approach offers a valuable tool for medical professionals in combating the COVID-19 pandemic.