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Updated: Aug 20, 2025

Ferritinophagy: Assessing the Selective Degradation of Iron by Autophagy in Human Fibroblasts
Published on: February 23, 2024
Extreme hyperferritinemia without associated HLH in a patient with T-cell lymphoma
Grace Lau1, Sean C Dougherty1, Lisa Friedman2
1Department of Internal Medicine University of Virginia Charlottesville Virginia USA.
Abstract:
Extreme hyperferritinemia has historically been associated with a short list of rare diagnoses, including hemophagocytic lymphohistiocytosis (HLH). However, hyperferritinemia is not specific for HLH in the adult population. Among other more common causes, T-cell lymphoma and other malignancies warrant evaluation prior to considering more rare diagnoses.
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