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Silica nanoparticle remodeling under mild conditions: versatile one step conversion of mesoporous to hollow
Cassandra C Shaffer1, Canjia Zhai1, Jordan L Chasteen1
1Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA. smith.115@nd.edu.
Nanoscale
|November 21, 2022
Abstract:
A binary mixture of mesoporous silica nanoparticles plus organic polyammonium additive (dye or drug) is cleanly converted upon mild heating into hollow nanoparticles. The remodeled nanoparticle shell is an organized nanoscale assembly of globular additive/silica subunits and cancer cell assays show that a loaded drug additive is bioavailable.
