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Updated: Aug 20, 2025

Mouse Model of Pressure Ulcers After Spinal Cord Injury
Published on: March 9, 2019
A Prospective Study of Pressure Injury Healing Rate and Time and Influencing Factors in an Acute Care Setting
YoungMin Seo1, HyunSoo Oh, YoungSun Na
1YoungMin Seo, PhD, RN, is Manager, Team of Core Medical Assessment and Build Standard, Inha University Hospital, Joong Gu, Incheon, Republic of Korea. HyunSoo Oh, PhD, RN, is Professor, Department of Nursing, Inha University, Incheon. YoungSun Na, BSN, RN, is Graduate Student, Department of Nursing, Inha University, and Wound Ostomy Care Nurse, Inha University Hospital. Also at Inha University Hospital, MiJin Kim, MSN, RN, is Wound Ostomy Care Nurse, and WhaSook Seo, PhD, is Professor, Department of Nursing, Inha University.
Objective:
To determine pressure injury (PI) healing rate and time and identify influencing factors.
Methods:
A prospective cohort research design was used. Data collection was performed between May 2015 and August 2018. The study participants were 77 inpatients who developed at least one PI during their stay in a university hospital. Researchers assessed participants' demographic (age, sex); physical (incontinence, activity of daily living, and nutrition status); physiologic (serum total protein, albumin, and creatinine, blood glucose, and hemoglobin levels); and disease- (diagnosis, number of comorbidities, and cardiovascular comorbidity), wound- (PI stage and size at first detection, and Pressure Ulcer Scale for Healing score), and treatment-related (IV nutrition supply and albumin infusion) factors.
Results:
Across the 77 patients, 91 PIs developed. Of these, 54 (59.3%) healed with a mean healing time of 17.63 days. The healing rate was better, and the healing time was shorter for stage 2 PIs compared with unstageable or deep-tissue PIs. Factors influencing PI healing rate were number of comorbidities, cardiovascular comorbidity, incontinence, PI stage at first detection, IV nutrition supply, and mean serum creatinine level. Factors influencing PI healing time were number of comorbidities, cardiovascular comorbidity, and PI stage at first detection.
Conclusions:
To reduce hospital stays, PI-related complications, and mortality, evidence-based management strategies for PIs are needed. The findings of the present study may contribute to the development of such strategies.
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