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In-hospital mortality of COVID-19 patients hospitalized with ST-segment elevation myocardial infarction: A

Huzaifa Ahmad Cheema1, Muhammad Ehsan1, Muhammad Ayyan1

  • 1Department of Medicine, King Edward Medical University, Lahore, Pakistan.

International Journal of Cardiology. Heart & Vasculature
|November 22, 2022
PubMed

Insights

COVID-19 infection significantly increases mortality and adverse outcomes in ST-segment elevation myocardial infarction (STEMI) patients. Early COVID-19 evaluation and aggressive management are crucial for improving prognosis in these high-risk individuals.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • COVID-19 is linked to cardiovascular complications, including thrombosis and myocardial injury.
  • Existing data show widely varying, elevated mortality risks for COVID-19 positive STEMI patients.
  • Inconsistencies in reported outcomes necessitate a comprehensive meta-analysis.

Purpose of the Study:

  • To assess the impact of COVID-19 infection on mortality in STEMI patients.
  • To evaluate other clinical outcomes in STEMI patients with COVID-19.
  • To resolve inconsistencies in the current literature regarding COVID-19 and STEMI outcomes.

Main Methods:

  • A systematic meta-analysis was conducted, adhering to Cochrane guidelines.
  • Searches of PubMed and Embase databases were performed up to April 2022.
  • Eleven studies comprising 435 initial records were included for analysis.

Main Results:

  • COVID-19 positive STEMI patients exhibited higher in-hospital mortality rates.
  • The risk of cardiogenic shock was elevated in STEMI patients with COVID-19.
  • Hospital stays were prolonged for STEMI patients who tested positive for COVID-19.

Conclusions:

  • Early COVID-19 status evaluation is essential for all STEMI patients.
  • Risk stratification and aggressive management are recommended for COVID-19 positive STEMI patients.
  • Further research is needed to understand the mechanisms of poorer prognosis.
Abstract

Keywords:
COVID-19MortalitySARS-CoV-2ST-segment elevation myocardial infarction

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