Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Blood cytotoxic natural killer-like CD8 + CD94+ T cells migrate to the brain and predict multiple sclerosis severity.

Brain : a journal of neurology·2026
Same author

Academic medicine career intentions among medical residents: a social cognitive career theory approach.

BMC medical education·2026
Same author

Detection of slowly expanding lesions in people with multiple sclerosis using MRI: A scoping review.

Imaging neuroscience (Cambridge, Mass.)·2026
Same author

A predictive tool for early treatment escalation after initiation of moderate-efficacy therapy in pediatric-onset multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)·2026
Same author

Spinal cord imaging for multiple sclerosis: Advances, priorities, and opportunities.

Multiple sclerosis (Houndmills, Basingstoke, England)·2026
Same author

Use of High-Efficacy Therapy in Children With Multiple Sclerosis to Prevent Long-Term Disability.

Neurology·2026
Same journal

A 57-Year-Old Male With Behavioral Variant Frontotemporal Dementia and MATR3 and NOS3 Mutations.

Annals of clinical and translational neurology·2026
Same journal

Reply to: A Lethal Progressive Neuroinflammation Disguised as MOGAD Revealing a Final Diagnosis of Griscelli Syndrome: Regarding: MOGAD is the Most Common Cause of Isolated Optic Neuritis in Children.

Annals of clinical and translational neurology·2026
Same journal

A Lethal Progressive Neuroinflammation Disguised as MOGAD Revealing a Final Diagnosis of Griscelli Syndrome.

Annals of clinical and translational neurology·2026
Same journal

Long-Term Neurologic Exam Findings in People Diagnosed and Treated During Acute HIV Infection.

Annals of clinical and translational neurology·2026
Same journal

Integrating Time-Adjusted Imaging Instability Into Functional Outcome Prediction After Intracerebral Hemorrhage: Development and Validation of the HAGIV Score.

Annals of clinical and translational neurology·2026
Same journal

Advancing Stroke Clinical Trials Using Community Engagement and Implementation Science Approaches.

Annals of clinical and translational neurology·2026
See all related articles

Related Experiment Video

Updated: Aug 20, 2025

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
10:46

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

10.7K

Multiple sclerosis clinical decision support system based on projection to reference datasets.

Chadia Ed-Driouch1,2, Florent Chéneau2, Françoise Simon1,3

  • 1Nantes Université, INSERM, CR2TI - Center for Research in Transplantation and Translational Immunology, F-44000, Nantes, France.

Annals of Clinical and Translational Neurology
|November 22, 2022
PubMed
Summary
This summary is machine-generated.

MS Vista uses computational power to personalize multiple sclerosis (MS) management. This clinical decision support system visualizes medication efficacy for relapsing-remitting MS (RRMS) patients, improving neurologist-patient communication.

More Related Videos

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
11:35

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

58.1K
Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
08:51

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Published on: February 19, 2021

9.1K

Related Experiment Videos

Last Updated: Aug 20, 2025

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
10:46

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

10.7K
The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
11:35

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

58.1K
Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
08:51

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Published on: February 19, 2021

9.1K

Area of Science:

  • Neurology
  • Medical Informatics
  • Computational Medicine

Background:

  • Multiple sclerosis (MS) presents complex management challenges due to its multifactorial nature.
  • Dynamic and personalized treatment strategies are crucial for effective MS care.
  • Current management approaches require enhanced tools for data integration and patient-specific insights.

Purpose of the Study:

  • To leverage on-demand computational power for dynamic management of multiple sclerosis.
  • To develop a clinical decision support system (CDSS) for personalized MS treatment.
  • To contextualize medication efficacy using individual patient data and reference cohorts.

Main Methods:

  • Utilized Phase 3 clinical trial data (NCT00906399) comparing peg-interferon beta-1a to placebo in relapsing-remitting MS (RRMS) patients.
  • Developed MS Vista, a CDSS with a user-centered design and distributed infrastructure.
  • Employed a set of reference patients (PORs) to personalize analytics for individual patient disease activity visualization (relapses, MRI lesions, EDSS).

Main Results:

  • MS Vista successfully visualizes individual patient medication efficacy for peg-interferon beta-1a versus placebo in RRMS.
  • The system integrates a longitudinal magnetic resonance imaging (MRI) viewer.
  • An interactive dual physician-patient data display was implemented to enhance communication.

Conclusions:

  • Pioneering the use of patient-specific reference cohorts (PORs) enables personalized analytics in MS management.
  • MS Vista sustains a dialog between neurologists, patients, and caregivers with quantified evidence.
  • This approach supports data-driven decision-making for improved MS patient outcomes.