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Updated: Aug 20, 2025

The Combined Use of Transcranial Direct Current Stimulation and Robotic Therapy for the Upper Limb
Published on: September 23, 2018
[Capabilities of combined therapy of Alzheimer's disease]
E E Vasenina1, N I Veryugina1, O S Levin1
1Russian Medical Academy for Continuous Professional Education, Moscow, Russia.
Abstract:
Alzheimer's disease is one of the most common neurodegenerative diseases worldwide and carries a huge social burden. Unfortunately, no disease-modifying drug has been approved so far. Currently approved medications are symptomatic and include two classes: cholinesterase inhibitors, such as donepezil, and NMDA receptor antagonist memantine. Most studies have shown that a combination of both classes is better than monotherapy. The review discusses the pharmacological properties, efficacy and safety data of memantine and donepezil.
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