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Updated: Aug 20, 2025

Capturing the Interaction Kinetics of an Ion Channel Protein with Small Molecules by the Bio-layer Interferometry Assay
Published on: March 7, 2018
Recent Advancements in Ion-Pair Receptors
Shafieq Ahmad Wagay1, Lubna Khan1, Rashid Ali1
1Organic and Supramolecular Functional Materials Research Laboratory, Department of Chemistry, Jamia Millia Islamia, Okhla, New Delhi, 110025, India.
Recent advancements in ion-pair receptors, a type of heteroditopic receptor, are revolutionizing host-guest chemistry. These receptors show significant potential in sensing, recognition, and purification applications, addressing critical health and environmental concerns.
Area of Science:
- Supramolecular Chemistry
- Non-covalent Chemistry
- Host-Guest Chemistry
Background:
- Non-covalent chemistry has developed artificial receptors, enhancing host-guest interactions.
- Supramolecular chemistry has yielded molecules for chemical, biological, environmental, and pharmacological applications.
- Heteroditopic receptors (ion-pair receptors) bind both cations and anions, attracting scientific interest.
Purpose of the Study:
- To review recent developments in ion-pair chemistry.
- To highlight the synthesis and diverse applications of ion-pair receptors.
- To provide insights into future prospects of ion-pair receptors.
Main Methods:
- Literature review of ion-pair chemistry.
- Discussion of synthesis strategies for ion-pair receptors.
- Exploration of applications including sensing, recognition, and molecular machines.
Main Results:
- Ion-pair receptors exhibit unique binding abilities for ionic entities.
- These receptors have demonstrated potential in sensing, recognition, transport, and extraction.
- Applications extend to salt/waste purification and molecular machines.
Conclusions:
- Ion-pair receptors are a rapidly developing area within supramolecular chemistry.
- Their unique properties offer solutions for various scientific and environmental challenges.
- Further research is expected to uncover novel opportunities and applications.
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