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Spontaneous regression in a primary adenocarcinoma of lung with epidermal growth factor receptor mutation
Farhan Ahmad1, Shalini Singh1, Niraj Kumari2
1Department of Radiotherapy, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Abstract:
Spontaneous regression (SR) has been reported sporadically in few tumor types. Its occurrence in non-small-cell lung cancer is relatively rare, more so with adenocarcinoma histology. Various mechanisms of SR have been postulated in literature that may play a role in triggering immune response. However, the exact underlying mechanism has yet to be ascertained. We report a rare case of true SR in a primary adenocarcinoma of lung with tumor-infiltrating lymphocytes and epidermal growth factor receptor mutation.
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