Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Acute Respiratory Failure-V01:29

Acute Respiratory Failure-V

182
The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
182
Acute Kidney Injury VI: Nursing Management01:22

Acute Kidney Injury VI: Nursing Management

45
Acute Kidney Injury (AKI) results in an inability to maintain fluid, electrolyte, and acid-base balance. Effective nursing management is critical in improving patient outcomes and includes comprehensive patient assessment and targeted interventions.Comprehensive Patient AssessmentA detailed history collection is essential, focusing on any recent infections, nephrotoxic medication use, or chronic conditions such as hypertension and diabetes that may contribute to AKI. During the physical...
45
Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

70
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
70
Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

120
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
120
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

40
Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
40
Liver Regeneration01:24

Liver Regeneration

3.3K
The liver is an important organ in vertebrates that plays an essential role in metabolism. It is also responsible for storing and redistributing nutrients such as carbohydrates, fats, and vitamins in the body. Additionally, the liver releases bile salts which are critical for digesting food and eliminating toxic metabolites from the body.
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are...
3.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cellular Metabolic Signatures of Long COVID-19.

Infectious disease reports·2026
Same author

Guar Gum, Partially Hydrolyzed Guar Gum, and Human Gut Health: A Narrative Review.

Reviews on recent clinical trials·2026
Same author

Metabolic Dysfunction-Associated Steatotic Liver Disease and Incretin Receptor Agonists: A Metabolic Approach to Halting Liver Disease Progression.

Medicina (Kaunas, Lithuania)·2026
Same author

Artificial Intelligence-Guided Artificial Nutrition in Critical Illness: Integrating Indirect Calorimetry and BIVA for Metabolic Precision.

Nutrients·2026
Same author

Gastrointestinal Health: Clinical Research and Therapeutic Innovations.

Life (Basel, Switzerland)·2026
Same author

Immunonutrition for the Management of Postsurgery GI Cancer Patients.

Nutrients·2026

Related Experiment Video

Updated: Aug 20, 2025

Generation of a Rat Model of Acute Liver Failure by Combining 70% Partial Hepatectomy and Acetaminophen
09:44

Generation of a Rat Model of Acute Liver Failure by Combining 70% Partial Hepatectomy and Acetaminophen

Published on: November 27, 2019

10.2K

Nutritional Support in Acute Liver Failure.

Ludovico Abenavoli1, Valentina Maurizi2, Luigi Boccuto3

  • 1Department of Health Sciences, University "Magna Græcia", 88100 Catanzaro, Italy.

Diseases (Basel, Switzerland)
|November 22, 2022
PubMed
Summary
This summary is machine-generated.

Nutrition is vital for acute liver failure (ALF) patients. Key strategies include branched-chain amino acids (BCAAs) and gut microbiota modulation, crucial for recovery and preventing complications.

Keywords:
branched-chain amino acidsdysbiosisgut microbiotaliver failurenutritionprobiotics

More Related Videos

The Murine Choline-Deficient, Ethionine-Supplemented CDE Diet Model of Chronic Liver Injury
07:27

The Murine Choline-Deficient, Ethionine-Supplemented CDE Diet Model of Chronic Liver Injury

Published on: October 21, 2017

11.9K
Author Spotlight: Evaluating Therapeutic Strategies to Enhance Liver Regeneration
05:25

Author Spotlight: Evaluating Therapeutic Strategies to Enhance Liver Regeneration

Published on: May 24, 2024

2.1K

Related Experiment Videos

Last Updated: Aug 20, 2025

Generation of a Rat Model of Acute Liver Failure by Combining 70% Partial Hepatectomy and Acetaminophen
09:44

Generation of a Rat Model of Acute Liver Failure by Combining 70% Partial Hepatectomy and Acetaminophen

Published on: November 27, 2019

10.2K
The Murine Choline-Deficient, Ethionine-Supplemented CDE Diet Model of Chronic Liver Injury
07:27

The Murine Choline-Deficient, Ethionine-Supplemented CDE Diet Model of Chronic Liver Injury

Published on: October 21, 2017

11.9K
Author Spotlight: Evaluating Therapeutic Strategies to Enhance Liver Regeneration
05:25

Author Spotlight: Evaluating Therapeutic Strategies to Enhance Liver Regeneration

Published on: May 24, 2024

2.1K

Area of Science:

  • Hepatology
  • Gastroenterology
  • Nutritional Science

Background:

  • Acute liver failure (ALF) is a severe condition characterized by rapid liver dysfunction without pre-existing chronic liver disease.
  • Nutritional management in ALF is critical but not fully understood, with potential impacts on gut microbiota.
  • Hepatic encephalopathy and coagulopathy are common complications of ALF.

Purpose of the Study:

  • To review existing literature on acute liver failure (ALF) and the role of nutrition in its prevention and treatment.
  • To explore the influence of gut microbiota dysbiosis and eubiosis in ALF.
  • To identify optimal nutritional strategies for ALF patients.

Main Methods:

  • Literature review conducted on major medical databases.
  • Keywords included: liver failure, nutrition, branched-chain amino acids (BCAAs), gut microbiota, dysbiosis, and probiotics.
  • Analysis focused on nutritional assessment, specific nutrient requirements, and the impact of gut health.

Main Results:

  • Early nutritional assessment is essential upon emergency department arrival for ALF patients.
  • Branched-chain amino acids (BCAAs), stable euglycemia, and moderate caloric intake are crucial.
  • Excessive protein intake should be avoided to prevent worsening hepatic encephalopathy.

Conclusions:

  • Nutritional support is a cornerstone in managing ALF, significantly impacting patient morbidity and mortality.
  • BCAAs and maintaining euglycemia are primary nutritional interventions for ALF.
  • Modulating gut dysbiosis shows promise as a future therapeutic strategy for ALF.