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Pharmacobezoar after overdose of isoniazid and rifampin
Marco Marano1,2, Davide Lonati3, Filippo Torroni4
1Pediatric Poison Control Center, Children's Hospital Bambino Gesù, IRCCS, Rome, Italy.
Abstract:
In clinical toxicology, gastric endoscopic decontamination is rarely used, and only a few cases of pharmacobezoar removal after intentional ingestion of slow-release drugs have been described. Our case describes the use of gastric endoscopic decontamination to remove potential pharmacobezoar in an adolescent after ingestion of a lethal dose of isoniazid and rifampin, even long after gastric lavage. This technique allowed the removal of pharmacobezoars still present in the stomach while preventing further deterioration of the patient.
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