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Association between Gestational Age, Birth Weight, Parental Age at Childbirth, Mode of Delivery, and Infantile

Junting Huang1, Qianwen Zheng2, Kailai Nie1

  • 1Department of Optometry and Visual Science, West China Hospital, Sichuan University, Chengdu, China.

Optometry and Vision Science : Official Publication of the American Academy of Optometry
|November 22, 2022
PubMed

Insights

Low birth weight and emergency cesarean deliveries are identified as significant risk factors for infantile esotropia in a Chinese population. These findings aid in developing targeted interventions for this common childhood eye condition.

Area of Science:

  • Ophthalmology
  • Perinatology
  • Pediatrics

Background:

  • Infantile esotropia is a common condition requiring early intervention.
  • Understanding perinatal risk factors is crucial for prevention and management.

Purpose of the Study:

  • To investigate associations between perinatal factors and infantile esotropia in a Chinese cohort.
  • To identify specific risk factors such as birth weight, parental age, and delivery mode.

Main Methods:

  • Case-control study involving 99 patients with infantile esotropia and 117 controls.
  • Data collected via parental questionnaires.
  • Logistic regression analysis to determine risk factors and their significance.

Main Results:

  • Low birth weight (<2500 g) was significantly associated with infantile esotropia (OR, 4.235; P = .008).
  • Emergency cesarean delivery also showed a significant association (OR, 2.230; P = .02).

Conclusions:

  • Low birth weight and emergency cesarean delivery are confirmed risk factors for infantile esotropia.
  • Emphasizes the need for integrated care among obstetric, pediatric, and vision specialists.
  • Findings support targeted interventions for high-risk infants.
Abstract

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