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Automated digital technologies for supporting sepsis prediction in children: a scoping review protocol
Ryan Tennant1, Jennifer Graham2, Kate Mercer3,4
1Department of Systems Design Engineering, University of Waterloo Faculty of Engineering, Waterloo, Ontario, Canada drtennan@uwaterloo.ca.
BMJ Open
|November 22, 2022
Summary
This scoping review examines automated digital technologies for predicting pediatric sepsis. It identifies current evidence, design characteristics, and factors influencing clinical integration to improve early detection and treatment.
Area of Science:
- Pediatric Sepsis Research
- Digital Health Technologies
- Clinical Decision Support Systems
Background:
- Limited reviews exist on digital sepsis prediction for children, unlike adults.
- A knowledge gap persists in automated technology development for pediatric sepsis prediction.
- This review addresses the need for evidence on digital tools for early sepsis detection in children.
Purpose of the Study:
- To critically analyze evidence on the design and performance of automated digital technologies for pediatric sepsis prediction.
- To identify factors influencing the clinical integration of these technologies.
- To advance the development and implementation of pediatric sepsis prediction tools.
Main Methods:
- Scoping review following Arksey and O'Malley's framework.
- Searches across multiple databases (ACM, CINAHL, Embase, Google Scholar, IEEE, PubMed, Scopus, Web of Science).
- Inclusion of studies on children aged >90 days to <21 years; thematic analysis of extracted data.
Main Results:
- The review will identify current evidence on digital pediatric sepsis prediction technologies.
- It will detail the design characteristics and performance metrics of these technologies.
- Factors influencing clinical integration will be elucidated.
Conclusions:
- This review will provide a comprehensive overview of the current landscape of digital pediatric sepsis prediction.
- Findings will inform the future development and clinical integration of these vital technologies.
- The study aims to improve timely and accurate sepsis detection in children.

