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Updated: Aug 20, 2025

Identifying DNA Mutations in Purified Hematopoietic Stem/Progenitor Cells
Published on: February 24, 2014
Hematologic and Oncologic Emergencies
Kyle Holden1, Sheldon Rao, Richard White
1Division of Pulmonary and Critical Care Medicine (Drs Holden, Rao, Bangash, Schmetzer, Sangli, and Balaan) and Cardiovascular Institute (Drs Ivanova and Madgula), Division of Hematology and Medical Oncology (Dr White) Allegheny Health Network, Pittsburgh, Pennsylvania.
Abstract:
This article reviews both hematologic and oncologic emergencies that may be seen in the intensive care setting. Hematologic emergencies, including autoimmune hemolytic anemia, thrombotic thrombocytopenic purpura, hemolytic uremic syndrome, and disseminated intravascular coagulation, as well as oncologic emergencies including tumor lysis syndrome, superior vena cava syndrome, and cardiac tamponade secondary to metastatic disease, are discussed in detail. This review focuses on the pathophysiology, clinical features, diagnosis, and treatment of each entity.
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