Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Origin and application of the Lorentz factor in X-ray diffraction.

Acta crystallographica. Section A, Foundations and advances·2026
Same author

Alumina Priming-Mediated Enhanced Binding of Diethylzinc with Carbonyl Groups in Poly(Methyl Methacrylate) during Vapor-Phase Infiltration.

Chemistry of materials : a publication of the American Chemical Society·2026
Same author

Machine Learning Framework for Characterizing Processing-Structure Relationship in Block Copolymer Thin Films.

Macromolecules·2026
Same author

Resonant Tender X‑ray Scattering for Disclosing the Backbone Conformation of Conjugated Polymers.

Macromolecules·2026
Same author

Resonant X-Ray Diffraction of Conjugated Polymers at the Selenium K-Edge.

Macromolecular rapid communications·2026
Same author

Pattern-enhanced Resonant Soft X-ray Scattering for Operando monitoring of electrochemical solid-liquid interfaces.

Nature communications·2026

Related Experiment Video

Updated: Aug 20, 2025

Printing Thermoresponsive Reverse Molds for the Creation of Patterned Two-component Hydrogels for 3D Cell Culture
10:49

Printing Thermoresponsive Reverse Molds for the Creation of Patterned Two-component Hydrogels for 3D Cell Culture

Published on: July 10, 2013

15.2K

Physical Models from Physical Templates Using Biocompatible Liquid Crystal Elastomers as Morphologically Programmable

Marianne E Prévôt1, Senay Ustunel1,2, Guillaume Freychet3

  • 1Advanced Materials and Liquid Crystal Institute, Kent State University, Kent, OH, 44242, USA.

Macromolecular Bioscience
|November 23, 2022
PubMed
Summary

Researchers developed a novel liquid crystal elastomer (LCE) bio-ink for 3D printing complex tissue models. This advanced material promotes cell growth and guides cellular alignment, overcoming key challenges in tissue engineering.

Keywords:
3D cell culture3D printing3D systemsadditive manufacturingdigital light processingliquid crystal elastomers

More Related Videos

Bioprintable Alginate/Gelatin Hydrogel 3D In Vitro Model Systems Induce Cell Spheroid Formation
16:20

Bioprintable Alginate/Gelatin Hydrogel 3D In Vitro Model Systems Induce Cell Spheroid Formation

Published on: July 2, 2018

18.7K
Synthesis of Biocompatible Liquid Crystal Elastomer Foams as Cell Scaffolds for 3D Spatial Cell Cultures
13:38

Synthesis of Biocompatible Liquid Crystal Elastomer Foams as Cell Scaffolds for 3D Spatial Cell Cultures

Published on: April 11, 2017

9.5K

Related Experiment Videos

Last Updated: Aug 20, 2025

Printing Thermoresponsive Reverse Molds for the Creation of Patterned Two-component Hydrogels for 3D Cell Culture
10:49

Printing Thermoresponsive Reverse Molds for the Creation of Patterned Two-component Hydrogels for 3D Cell Culture

Published on: July 10, 2013

15.2K
Bioprintable Alginate/Gelatin Hydrogel 3D In Vitro Model Systems Induce Cell Spheroid Formation
16:20

Bioprintable Alginate/Gelatin Hydrogel 3D In Vitro Model Systems Induce Cell Spheroid Formation

Published on: July 2, 2018

18.7K
Synthesis of Biocompatible Liquid Crystal Elastomer Foams as Cell Scaffolds for 3D Spatial Cell Cultures
13:38

Synthesis of Biocompatible Liquid Crystal Elastomer Foams as Cell Scaffolds for 3D Spatial Cell Cultures

Published on: April 11, 2017

9.5K

Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Advanced Manufacturing

Background:

  • Developing biocompatible and biodegradable materials for 3D printing cell scaffolds that guide cell alignment is a significant challenge.
  • Existing methods struggle to meet the precise parameters required for fabricating complex, functional tissue models.

Purpose of the Study:

  • To present a photocrosslinkable smectic-A (Sm-A) liquid crystal elastomer (LCE) bio-ink for 3D printing.
  • To demonstrate the LCE's ability to promote cell proliferation and induce cell anisotropy.
  • To create complex vascular tissue models with aligned cells.

Main Methods:

  • Fabrication of a photocrosslinkable Sm-A liquid crystal elastomer (LCE) bio-ink.
  • 3D printing of complex vascular tissue models using Digital Light Processing (DLP) stereolithography (SLA).
  • Characterization of LCE alignment using Synchrotron Small-Angle X-ray Diffraction (SAXD).
  • Assessment of cell growth and alignment within the printed scaffolds.

Main Results:

  • The LCE-based bio-ink successfully replicated complex 3D vascular tissue structures.
  • SAXD data confirmed strong alignment of LCE layering within the printed scaffold struts.
  • The anisotropic LCE struts effectively directed cell growth and alignment.
  • The 3D printed models promoted cell proliferation.

Conclusions:

  • A novel LCE bio-ink offers a promising solution for advanced tissue engineering.
  • The developed material and 3D printing approach enable rapid fabrication of cell-guiding tissue models.
  • This method simplifies the production of complex, cell-aligned tissue constructs within hours.