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Arrhythmia related to hypertensive left ventricular hypertrophy in Iraqi patients: frequency and outcome
1College of Medicine, University of Baghdad, Baghdad, Iraq.
Insights
Hypertension-induced left ventricular hypertrophy (LVH) significantly increases arrhythmia risk. This study found 16.3% of hypertensive patients with LVH experienced arrhythmias, most commonly atrial fibrillation and premature ventricular contractions.
Area of Science:
- Cardiology
- Internal Medicine
- Clinical Research
Background:
- High blood pressure is a leading cause of left ventricular hypertrophy (LVH).
- LVH is associated with increased risks of mortality and cardiac arrhythmias.
- Understanding arrhythmia prevalence in hypertensive patients with LVH is crucial for risk stratification.
Purpose of the Study:
- To evaluate the frequency and types of cardiac arrhythmias in hypertensive patients with left ventricular hypertrophy (LVH).
- To identify clinical characteristics associated with arrhythmia in this patient population.
Main Methods:
- Cross-sectional study involving 300 hypertensive adult patients (>18 years).
- Assessment included blood pressure, echocardiography, electrocardiography, and Holter monitoring (select cases).
- Data collected between January and June 2022 at a cardiology unit.
Main Results:
- Overall, 16.3% of hypertensive patients had arrhythmia.
- Patients with arrhythmia were older and had a higher prevalence of LVH (24.5%) and cardiac failure.
- Common arrhythmias included atrial fibrillation (AF), atrial flutter, and premature ventricular contractions (PVCs).
Conclusions:
- Hypertensive patients with LVH exhibit a significant frequency of cardiac arrhythmias.
- Arrhythmia in this cohort is linked to older age, LVH, and cardiac failure.
- Atrial fibrillation and premature ventricular contractions are the most prevalent arrhythmias observed.
Abstract:
Left ventricular hypertrophy (LVH) caused by high blood pressure is linked to increased mortality and arrhythmia risk. This study aimed to evaluate arrhythmia in hypertensive patients due to left ventricular hypertrophy (LVH). A cross-sectional study was performed, assessing participants' blood pressure, echocardiography and electrocardiography, and Holter monitoring in certain cases. There were 300 hypertensive patients >18 years attending the cardiology unit of Baghdad medical city. The study was conducted between January-June 2022. The electrocardiograms at rest for 300 adults with hypertension were investigated. 130 (43.5%) were females, and 170 (56.5%) were males. The mean age of participants was 58 years. Forty-nine (16.3%) patients had arrhythmia. As compared to those without arrhythmia, participants with arrhythmia were older (62.3 vs. 56.1, p=0.03), had a greater prevalence of left ventricular hypertrophy (24.5% vs. 12.7%, p=0.026), and more prone to experience cardiac failure (32.7% vs. 8.5%, p<0.011). Atrial fibrillation was found in 6 (27.2%) female patients and 5 (18.5%) males. In addition, two (7.4%) male patients and one female patient (4.5%) had atrial flutter, and premature ventricular contractions (PVCs) were noted in 10 (37%) and 11 (50%) patients. Left ventricular mass index (LVMI) was 103 gm/m2 in female patients and 119.2 gm/m2 in males. Palpitation was present in 22 (44.9%) female patients and 27 (55.1%) males. The study revealed that hypertensives with LVH have an arrhythmia frequency of 16.3%. The most common arrhythmias were atrial fibrillation and premature ventricular complex.
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