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Promising Adjunct Medicines in the Protocol of COVID-19 Clinical Trial
Mona Mahmoud AbouSamra1, Soheir Said Mansy2
1Pharmaceutical Technology Department, Pharmaceutical and Drug Industries Research Division, National Research Centre, Cairo, 12622 Egypt.
Abstract:
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative organism of COVID-19. Since this disease is considered new and does not have an approved curative protocol, many researchers have tackled the possible options for COVID-19 prevention and therapeutic approaches. We address herein the phenomena of cytokine storm (the main cause of death) associating with the late stage of COVID19. Cytokine storm is undertaken in an attempt to provide information about its possible underlying causes, and to clarify some points that can be of value in guiding treatment practices for a clinical trial.
Insights
This study examines the cytokine storm, a major cause of death in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients. Understanding cytokine storm mechanisms is crucial for developing effective COVID-19 treatments.
Area of Science:
- Immunology
- Virology
- Critical Care Medicine
Background:
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19, a novel disease lacking established curative protocols.
- The cytokine storm, an overactive immune response, is identified as the primary cause of mortality in severe COVID-19 cases.
- Current research focuses on prevention and therapeutic strategies due to the novelty of the disease.
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