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Thirty novel sequence variants impacting human intracranial volume

Muhammad Sulaman Nawaz1,2, Gudmundur Einarsson1, Mariana Bustamante1

  • 1deCODE genetics/Amgen Inc., Sturlugata 8, 102 Reykjavik, Iceland.

Brain Communications
|November 23, 2022
PubMed
Summary

Genome-wide analysis identified 64 variants influencing intracranial volume, a heritable trait linked to brain function and neurological conditions. These findings shed light on genes affecting brain size and associated disorders like Parkinson's disease.

Keywords:
Mendelian randomizationbrain structuregenetic correlationgenome-wide association studyintracranial volume

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