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1Department of Computer Science Engineering, Amity University Chhattisgarh, Manth, Kharora, Baloda Bazar Road, Raipur, 493225, Chhattisgarh, India. rkashyap@rpr.amity.edu.
Journal of Digital Imaging
|November 23, 2022
Summary
This study enhances deep learning for breast cancer screening by addressing overfitting and color variation in histopathology images. The new method improves diagnostic accuracy, outperforming existing techniques.
Area of Science:
- Medical Imaging
- Artificial Intelligence
- Computational Pathology
Background:
- Standardizing breast cancer screening is a significant challenge in modern medicine.
- Deep learning models show promise in distinguishing between benign and malignant tumors.
- Histopathology images present difficulties due to color variations from staining and biopsy materials, leading to inaccurate diagnoses.
Purpose of the Study:
- To address overfitting and color divergence in deep learning models for breast cancer classification.
- To develop a novel method for extracting and enhancing fine-grained features in histopathology images.
- To improve the reliability of deep learning models in recognizing very small objects for accurate breast cancer diagnosis.
Main Methods:
- Strain normalization and adding extra components were used to rectify overfitting and color divergence.
- A multiscale stochastic and dilation unit was developed for extracting fine-grained features at various image scales.
- A stochastic pooling block with convolution and identity mapping was employed to maintain feature mappings and reduce dimensionality.
Main Results:
- The proposed methods successfully addressed overfitting and color divergence issues.
- The multiscale unit effectively extracted edges, contours, and improved color accuracy.
- The enhanced model demonstrated superior performance compared to existing methods, achieving an area under the curve of 96.15%.
Conclusions:
- The developed deep learning approach offers a more accurate and reliable method for breast cancer screening.
- Addressing image variations and enhancing feature extraction are crucial for improving diagnostic performance.
- The proposed techniques show significant potential for standardizing and advancing breast cancer diagnosis through artificial intelligence.

