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Current Practice in Carcinoid Heart Disease and Burgeoning Opportunities
Carrie Lenneman1, David Harrison2, S Lindsey Davis3
1Division of Cardiology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Opinion Statement:
Cardiac surgery with tricuspid valve and potentially pulmonic valve replacement at an experienced center is currently the most effective strategy available for the treatment of carcinoid heart disease. Cardiac surgery for carcinoid heart disease requires a multidisciplinary team including cardiology, medical oncology, cardiothoracic anesthesia, and cardiac surgery. Without cardiac surgery, morbidity and mortality from carcinoid heart disease is high. Aggressive management of carcinoid before and after cardiac surgery is critical. Over time, though, circulating carcinoid hormones can lead to destruction of prosthetic valves as well, resulting in recurrent right heart failure. Percutaneous options for valve repair may be on the horizon for management of carcinoid heart disease.
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