Prospective bacterial and fungal sources of hyaluronic acid: A review

E V Shikina1,2, R A Kovalevsky1, A I Shirkovskaya1

  • 1N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky prospect 47, 119991 Moscow, Russian Federation.

Keywords:
ATP, adenosine triphosphateCSDB, Carbohydrate Structure DatabaseDO, dissolved oxygenFDA, Food and Drug administrationGAG, glycosaminoglycanGRAS, generally recognized as safeGlc, glucoseGlcpA, glucuronic acidGlcpNAc, N-acetylglucosamineGram-positive bacteriaHA, hyaluronic acidHAS, hyaluronic acid synthaseHW HA, high-molecular weight hyaluronic acidHYBID, hyaluronan-binding protein involved in HA depolymerizationHyaluronic acidLW HA, low-molecular weight hyaluronic acidMMP-2, matrix metalloproteinase 2MW, molecular weightMicrobial fermentationMurNAc, N-acetylmuramic acidND, no dataRHAMM, receptor for hyaluronic acid mediated motilityRecombinant organismSNFG, symbol nomenclature for glycansUDP, uridine 5′-trihydrogen diphosphateUMP, 5′-uridylic acidUTP, uridine-5′-triphosphateamyE, α-amylase (B. subtilis)aprE, subtilisin E (B. subtilis)araR, repressor of arabinose operonscat, acetyl-CoA:CoA transferasedcas9, dead Cas9 (derived from S. pyogenes)eglS, endoglucanase (B. subtilis)epr, minor extracellular protease (B. subtilis)galR, HTH-type transcriptional regulator GalR (E. coli)galS, HTH-type transcriptional regulator GalS (E. coli)galU, UTP-glucose-1-phosphate uridylyltransferaseglmM, phosphoglucosamine mutaseglmS, l-glutamine-d-fructose-6-phosphate aminotransferaseglmU, bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase (Corynebacterium glutamicum)kfiD, UDP-glucose 6-dehydrogenaselacA (ganA), β-galactosidase (B. subtilis)ldh, lactate dehydrogenasemazF, endoribonuclease (E. coli)mpr, extracellular metalloprotease (B. subtilis)nprB, neutral protease B (B. subtilis)nprE, bacillolysin (B. subtilis)pfkA, ATP-dependent 6-phosphofructokinase (E. coli)pgcA, phosphoglucomutasepoxB, pyruvate:quinone oxidoreductasepta-ackA operon, phosphate acetyltransferase and acetate kinasesigF, RNA polymerase sigma-F factor (B. subtilis)thrC, threonine synthase (B. subtilis)tuaD, UDP-glucose 6-dehydrogenase (1)udgA, UDP-glucose 6-dehydrogenase (2)upp, uracil phosphoribosyltransferase (B. subtilis)vHMW HA, very-high-molecular weight hyaluronic acidwprA, cell wall associated protease (B. subtilis)xylR, xylose operon repressor (B. megaterium)zwf, glucose-6-phosphate 1-dehydrogenase