Surgical Treatment Using Artificial Dermis for Women with Locally Advanced Breast Cancer

Area of Science:

• Oncology
• Surgical Oncology
• Palliative Care

Background:

• Locally advanced breast cancer (LABC) presents significant challenges for physicians and patients, causing distress through tumor growth, skin invasion, bleeding, and odor.
• Managing LABC symptoms and selecting appropriate therapeutic options can be difficult for clinicians.

Purpose of the Study:

• To evaluate the clinical outcomes of patients treated with total resection of LABC and artificial dermis (TERUDERMIS).
• To assess the efficacy of the TERUDERMIS procedure in palliating symptoms and reducing complications associated with LABC.

Main Methods:

• The study reviewed the clinical courses of patients who underwent total resection of LABC combined with the attachment of artificial dermis (TERUDERMIS).
• Outcomes were assessed based on symptom elimination, tumor recurrence, and overall patient condition post-surgery.

Main Results:

• The TERUDERMIS procedure successfully eliminated tumor-derived symptoms in all patients.
• Most patients remained alive with no signs of tumor recurrence, except for one patient with initial bone metastasis who survived 13 months post-operation.
• The treatment demonstrated reliability in managing infections and hemorrhage associated with LABC.

Conclusions:

• Surgical resection combined with artificial dermis (TERUDERMIS) is a reliable and effective method for palliating symptoms in LABC patients.
• This approach offers significant benefits to both patients and physicians by reducing symptom burden and simplifying post-operative care.
• TERUDERMIS provides a valuable option for managing complex LABC cases, improving quality of life and reducing the need for extensive supportive care.