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Neurodevelopmental Outcomes among Brazilian Children with Cyanotic Congenital Heart Disease and Its Associated

Flávia Saraçol Vignol1, Priscila Aikawa1, Tatiane Britto da Silveira2

  • 1Faculty of Medicine, Universidade Federal do Rio Grande-FURG, Rio Grande 96203-900, Brazil.

Medicina (Kaunas, Lithuania)
|November 24, 2022
PubMed

Insights

Children with cyanotic congenital heart disease (CHD) showed no significant differences in neurodevelopmental outcomes compared to healthy peers. However, socioeconomic factors impacted intelligence and attention in all children studied.

Area of Science:

  • Pediatric Cardiology
  • Developmental Pediatrics
  • Public Health

Background:

  • Cyanotic congenital heart disease (CHD) can impact child development.
  • Understanding neurodevelopmental outcomes in these children is crucial for early intervention and support.
  • Limited research exists on neurodevelopmental outcomes in Brazilian children with cyanotic CHD.

Purpose of the Study:

  • To compare neurodevelopmental outcomes (motor, intelligence, attention) in children with cyanotic CHD versus healthy children.
  • To identify factors associated with neurodevelopmental deficits in this pediatric population.
  • To inform public health policies for child health in Brazil.

Main Methods:

  • Cross-sectional study involving 37 children with cyanotic CHD and 38 healthy controls.
  • Utilized questionnaires, SNAP IV scale for attention, R-2 Non-Verbal Intelligence test, and a motor development scale.
  • Poisson regression analysis with robust estimation was employed to identify associated factors.

Main Results:

  • No statistically significant differences were found in motor development, nonverbal intelligence, or attention between children with cyanotic CHD and the control group.
  • Low socioeconomic status was linked to poorer performance in intelligence and attention.
  • Older age was associated with better intelligence test performance, and more siblings with worse attention.

Conclusions:

  • Cyanotic CHD itself did not appear to be a significant predictor of neurodevelopmental deficits in this cohort.
  • Socioeconomic conditions and family size are important factors influencing neurodevelopment in children.
  • Public health policies should address social determinants of health to improve child well-being.

Keywords:
child developmentcyanosiseducationheart diseases

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