Related Experiment Video
Updated: Aug 20, 2025

Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
Insulin Pump Therapy Efficacy and Key Factors Influencing Adherence in Pediatric Population-A Narrative Review
Laura Mihaela Trandafir1,2, Stefana Maria Moisa1,2, Mihaela Victoria Vlaiculescu3
1Pediatrics Department, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.
Insights
Improving pediatric adherence to insulin pump therapy is crucial for better glycemic control. Addressing factors affecting adherence, like communication and support, enhances diabetes management in children.
Area of Science:
- Pediatric Endocrinology
- Diabetes Management
- Medical Adherence Research
Background:
- Insulin pump therapy is a key treatment for type 1 diabetes in children.
- Optimizing adherence to insulin pump therapy is essential for effective disease management.
- Understanding factors influencing adherence is critical for improving patient outcomes.
Purpose of the Study:
- To review the current state of pediatric adherence to insulin pump therapy.
- To identify and minimize factors negatively impacting adherence in the pediatric population.
- To emphasize the importance of adherence for juvenile diabetes management.
Main Methods:
- Systematic literature search of PubMed, Embase, and Science Direct databases.
- Utilized keywords: adherence, pump insulin therapy, children, pediatric population, type 1 diabetes, and synonyms.
- Evaluated articles focusing on factors affecting insulin pump adherence in children.
Main Results:
- Better adherence to diabetes management correlates with improved glycemic control.
- Identified numerous variables that hinder adherence to insulin pump therapy regimens.
- Key factors for improved adherence include: effective provider-patient communication (telehealth), continuous education, family support, and societal assistance.
Conclusions:
- Obstacles to optimal insulin pump adherence in young patients present intervention opportunities.
- Improving adherence can lead to enhanced glycemic control.
- Successfully addressing adherence challenges significantly improves the quality of life for pediatric patients with type 1 diabetes.
Abstract:
Objective: we aimed to highlight the state of the art in terms of pediatric population adherence to insulin pumps. This study intends to underline the significance of identifying and minimizing, to the greatest extent feasible, the factors that adversely affect the juvenile population's adherence to insulin pump therapy. Materials and methods: articles from PubMed, Embase, and Science Direct databases were evaluated using the following search terms: adherence, pump insulin therapy, children, pediatric population, and type 1 diabetes, in combination with several synonyms such as compliance, treatment adherence, pump adherence, patient dropouts, and treatment refusal. Results: A better glycemic control is connected to a better adherence to diabetes management. We identify, enumerate, and discuss a number of variables which make it difficult to follow an insulin pump therapy regimen. Several key factors might improve adherence to insulin pump therapy: efficient communication between care provider and patients (including home-based video-visits), continuous diabetes education, family support and parental involvement, as well as informational, practical assistance, and emotional support from the society. Conclusions: every cause and obstacle that prevents young patients from adhering to insulin pumps optimally is an opportunity for intervention to improve glycemic control and, as a result, their quality of life.
Related Concept Videos
Insulin: Dosing Regimen and Adverse Effects
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
Insulin Formulations: Types and Delivery
Short-acting insulins are divided into...
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Glucose Homeostasis: Pancreatic Islets and Insulin Secretion
Insulin and C-peptide are...
Glucagon-like Receptor Agonists
GLP-1, when administered in high doses intravenously, triggers insulin secretion, inhibits glucagon release, slows gastric emptying, reduces food intake, and restores normal insulin secretion. However, its rapid inactivation by...

