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Updated: Aug 20, 2025

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18F-Labeling of Radiotracers Functionalized with a Silicon Fluoride Acceptor SiFA for Positron Emission Tomography
Published on: January 11, 2020
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A cost effective method for the preparation of sodium fluoride [18F]NaF for PET-CT imaging by using an in-house
Manoj Kumar Singh1, Raviteja Nanabala1, Anees K Muhammed1
1Molecular Cyclotrons Pvt Ltd, Puthuvype, Ernakulam, Kerala, 682508, India.
Abstract:
We report the development of a manual module for the preparation of [18F]NaF for metastatic bone cancer imaging. By using this simple module, [18F]NaF production can be carried out inexpensively without using commercially available kits. The module can be used for making [18F]NaF from freshly irradiated H218O water or with left over activity in the target after [18F]FDG production. The product meets all quality control parameters.
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