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Acute necrotic arachnidism with necrotising fasciitis and recurrent pneumothorax
Jasleen Duggal1, Swathi Sunil Rao2, Shiva Kumar Reddy1
1Paediatrics, Nitte(Deemed to be University), KS Hegde Medical Academy, Mangalore, Karnataka, India.
Insights
Acute spider envenomation caused severe necrotizing fasciitis and lung injury in an infant. This case highlights the critical need to consider spider bites in unexplained, rapidly progressing infections.
Area of Science:
- Toxicology
- Dermatology
- Pediatrics
Background:
- Necrotizing fasciitis is a severe bacterial infection requiring prompt surgical and antibiotic treatment.
- Spider envenomation is a less common cause of soft tissue necrosis, with varying clinical presentations.
Observation:
- An infant presented with rapidly progressive fasciitis and dermo-myonecrosis following a suspected brown recluse spider (Loxosceles) bite.
- The condition rapidly involved deeper tissues, leading to lung parenchyma necrosis, pneumatoceles, and respiratory failure.
Findings:
- The infant developed severe necrotizing fasciitis and acute respiratory distress syndrome (ARDS) secondary to presumed Loxosceles envenomation.
- Despite aggressive medical and surgical management, including ventilation and antibiotics, the infant experienced refractory hypoxemia and succumbed.
Implications:
- This is the first reported fatal case of acute spider envenomation in India, emphasizing the potential severity of Loxosceles bites.
- Clinicians should consider spider envenomation in cases of rapidly progressive, antibiotic-unresponsive necrotizing fasciitis, especially in endemic areas.
Abstract:
A male infant presented with swelling of the left leg and fever. Over the next 2 days, the area developed fasciitis extending to the left thigh, abdomen, and lower chest. Meanwhile, the parents found a giant brown spider within the infant's cot belonging to the genus Loxosceles, otherwise called the brown recluse spider. The dermo-myonecrosis progressed to deeper tissues involving the lung parenchyma requiring invasive ventilation. CT of the thorax showed multiple pneumatoceles, and lung biopsy showed alveolar necrosis. The infant was treated with intravenous antibiotics and corticosteroids. We drained the pneumothoraces by thoracostomy and insertion of intercostal drainage tubes. The infant required respiratory support initially by conventional ventilation, which was escalated to high-frequency oscillatory ventilation. He had refractory hypoxaemia and died. This is the first fatal case of acute spider envenomation described in India. Spider envenomation must be considered in patients with sudden onset, rapidly progressive necrotising fasciitis unresponsive to antibiotic therapy.
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