Related Experiment Video
Updated: Aug 20, 2025

A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
Depression symptoms and quality of life in empty-nest elderly among Chengdu: A cross-sectional study
Lanying He1, Jian Wang1, Feng Wang1
1Department of Neurology, The Second People's Hospital of Chengdu, Chengdu, China.
Objectives:
To estimate the prevalence of depression symptoms and quality of life (QoL) and examined the influence of factors in the empty nest elderly.
Methods:
This was a cross-sectional study, which was conducted from February 2022 to May 2022. We recruited a convenience sample of no empty-nest elderly and empty-nest elderly (≥60 years) living in Chengdu. QoL was assessed using WHOQOL-BREF, Geriatric Depression Scale (GDS-15) was used to assess depression symptoms. Multivariable logistic regression was used to analyze data between independent variables with depression symptoms.
Results:
Two thousand twenty-six participants were included in this study, 39.0% (660/1,082) experienced depression symptoms among empty-nest elderly. Age (aOR, 1.02; 95% CI, 1.00-1.04; P = 0.046), chronic disease≥2 (aOR, 3.29; 95% CI, 2.50-4.33; P < 0.001) were associated with increased risk of depression symptoms, and physical activity (aOR, 0.59; 95% CI, 0.40-0.87; P = 0.008), physical health (aOR, 0.93; 95% CI, 0.88-0.99; P = 0.026), psychological health (aOR, 0.93; 95% CI, 0.87-0.98; P = 0.013), and total score (aOR, 0.97; 95% CI, 0.96-0.99; P < 0.001) were associated with decreased risk of depression symptoms among empty-nest elderly.
Conclusions:
Depression symptoms are common mental health problems among empty-nest elderly. We found that age, chronic disease ≥2 and physical activity were important factors that have an impact on depressive symptoms. Empty-nest elderly would have lowered QoL score.
Related Concept Videos
Erikson's Theory on Socioemotional Development during Adulthood
Intimacy Versus Isolation in Early Adulthood
Individuals in early...
Depressive Disorders: MDD and Dysthymia
Negative and Cognitive Symptoms of Schizophrenia
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Long-term Depression
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Cognitive Development During Adulthood

