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Pulmonary embolism and gastric bleed with disseminated mucormycosis - treading dangerous waters
Nishant Kumar Chauhan1, Ashish Agarwal2, Naveen Dutt3
1Department of Pulmonary Medicine, All India Institute of Medical Sciences (AIIMS), Jodhpur. nishant97@gmail.com.
Abstract:
Mucormycosis is an opportunistic infection seen in immunocompromised patients or in surgical and trauma settings with Mucorales wound contamination. In immunocompetent people, disseminated mucormycosis is uncommon. To ensure survival, patients with mucormycosis require early diagnosis and aggressive treatment using a multi-modality approach. We present a case of disseminated mucormycosis in an immunocompetent patient who also had pulmonary embolism and gastrointestinal bleeding. A recent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, identified retrospectively by a positive IgM against SARS-CoV-2, was the only risk factor present. This report emphasizes the increased risk of mucormycosis and thromboembolic complications following a recent SARS-CoV-2 infection, as well as its successful treatment with medical therapy alone.
Insights
Disseminated mucormycosis, a rare fungal infection, can occur in immunocompetent individuals after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Early diagnosis and medical treatment are crucial for managing this opportunistic infection and associated complications.
Area of Science:
- Mycology
- Infectious Diseases
- Critical Care Medicine
Background:
- Mucormycosis is a severe opportunistic fungal infection primarily affecting immunocompromised individuals.
- Disseminated mucormycosis is rare in immunocompetent hosts.
- Recent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been anecdotally linked to mucormycosis.
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