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An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Published on: February 8, 2019
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Bilateral posterior scleritis due to giant cell arteritis
Ayesha Karimi1, Tsz Lun Ernest Wong2, Guy Negretti2
1Department of Ophthalmology, Surrey and Sussex Healthcare NHS Trust, Redhill, Surrey, UK ayeshakarimi@nhs.net.
BMJ Case Reports
|November 25, 2022
Summary
Giant cell arteritis can cause potentially blinding posterior scleritis, even in patients with learning difficulties. Early recognition of subtle symptoms is crucial for timely diagnosis and preventing vision loss.
Area of Science:
- Ophthalmology
- Rheumatology
- Geriatrics
Background:
- Giant cell arteritis (GCA) is a systemic vasculitis primarily affecting older adults, potentially leading to irreversible vision loss.
- Posterior scleritis, an inflammation of the posterior sclera, can present with non-specific symptoms, often delaying diagnosis.
- Individuals with learning difficulties may have challenges communicating symptoms, further complicating early detection.
Observation:
- A woman in her mid-70s with mild learning difficulty presented with eye symptoms, headache, and shoulder pain.
- Despite consultations in General Practice and Accident & Emergency, her symptoms persisted for 11 days.
- Diagnoses considered included acute angle closure glaucoma and iritis, highlighting the diagnostic challenge.
Findings:
- The patient was diagnosed with bilateral posterior scleritis secondary to giant cell arteritis.
- This case underscores the potential for delayed diagnosis of posterior scleritis due to ambiguous presentation.
- The diagnosis was confirmed after a thorough ophthalmic assessment.
Implications:
- Prompt and thorough assessment of painful red eyes is essential, especially in patients with atypical presentations or communication challenges.
- Recognizing red-flag signs associated with GCA and posterior scleritis can facilitate earlier treatment and improve patient outcomes.
- Awareness of specific guidance for managing visual disturbances in individuals with learning difficulties is vital for healthcare providers.
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