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Three-Dimensional Constructive Interference in Steady State (3D CISS) Imaging and Clinical Applications in Brain
Marco Cavallaro1, Alessandra Coglitore1, Agostino Tessitore1
1Department of Biomedical Sciences and Morphological and Functional Imaging, University of Messina, Via Consolare Valeria 1, 98100 Messina, Italy.
Biomedicines
|November 26, 2022
Summary
Three-dimensional constructive interference in steady state (3D CISS) MRI offers high resolution and contrast for brain imaging. This review details its applications in diagnosing various neurological conditions, aiding radiologists in clinical practice.
Area of Science:
- Radiology
- Neuroimaging
Background:
- Three-dimensional constructive interference in steady state (3D CISS) is a magnetic resonance imaging (MRI) sequence.
- It is increasingly utilized for studying brain diseases due to its advanced capabilities.
Purpose of the Study:
- To review the fundamental physical principles of 3D CISS MRI.
- To detail the diverse applications of 3D CISS in brain imaging.
- To assist radiologists in optimizing 3D CISS for clinical practice.
Main Methods:
- Review of fundamental physical principles of 3D CISS MRI.
- Examination of various clinical applications in brain imaging.
- Inclusion of representative case studies.
Main Results:
- 3D CISS provides very high spatial resolution.
- It demonstrates strong cerebrospinal fluid signal hyperintensity.
- It achieves a high contrast-to-noise ratio, beneficial for various pathologies.
Conclusions:
- 3D CISS is versatile, applicable to cranial nerves, ventricular system, and subarachnoid cisterns.
- Emerging applications include acute ischemic stroke, vascular malformations, infections, and brain tumors.
- Enhanced understanding and application of 3D CISS can improve diagnostic accuracy in daily radiology.
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