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Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
Quinones as an Efficient Molecular Scaffold in the Antibacterial/Antifungal or Antitumoral Arsenal
Marcos Aurelio Dahlem Junior1, Ronald W Nguema Edzang1,2, André Luis Catto1,3
1Aix-Marseille Université, CNRS, CINaM, 13009 Marseille, France.
Abstract:
Quinone-based compounds constitute several general classes of antibiotics that have long shown unwavering efficiency against both Gram-positive and Gram-negative microbial infections. These quinone-based antibiotics are increasingly popular due to their natural origins and are used in natural beverages from herbs or plants in African, Chinese and Indian traditional medicines to treat and prevent various diseases. Quinone-based antibiotics display different bioactive profiles depending on their structures and exert specific biocidal and anti-biofilm properties, and based on recent literature, will be discussed herein.
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