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Pregnancy and COVID-19.

Thomas Ntounis1, Ioannis Prokopakis1, Antonios Koutras1

  • 11st Department of Obstetrics and Gynecology, National and Kapodistrian University of Athens, General Hospital of Athens 'ALEXANDRA', Lourou and Vasilissis Sofias Ave, 11528 Athens, Greece.

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Summary

Pregnant women face higher risks from SARS-CoV-2 (COVID-19), leading to adverse outcomes for both mother and baby. Prevention and treatment are crucial for better maternal and fetal health.

Keywords:
COVID-19SARS-CoV-2maternal outcomesneonatal outcomesobstetric outcomespregnancyvaccination

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Area of Science:

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Maternal-Fetal Medicine

Background:

  • Pregnancy alters physiological pathways, increasing susceptibility to infections like SARS-CoV-2.
  • Pregnant individuals are a high-risk group for severe COVID-19 complications.

Purpose of the Study:

  • To summarize the risks of SARS-CoV-2 infection in pregnancy.
  • To highlight adverse maternal and fetal outcomes associated with COVID-19 in expecting women.

Main Methods:

  • Review of current scientific evidence and research findings.
  • Analysis of reported maternal and fetal complications linked to SARS-CoV-2.

Main Results:

  • SARS-CoV-2 infection is associated with increased maternal risks including pneumonia and ICU admission.
  • Adverse fetal outcomes include miscarriage, stillbirth, preterm labor, pre-eclampsia, and intrauterine growth restriction.
  • Severe COVID-19 in pregnancy often impacts delivery timing and mode.

Conclusions:

  • Preventing SARS-CoV-2 infection is vital for pregnant individuals.
  • Pharmacological interventions should focus on mitigating risks and improving maternal, obstetric, and neonatal outcomes.