Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Amino Acid-Coated Nanoparticles for Preservation of Cut Roses: Formulation and Performance.

ACS omega·2026
Same author

Radiopaque coating for improved implantability and <i>in vivo</i> imaging of neural probes.

Journal of materials chemistry. B·2026
Same author

Dual NIR-I excitation and emission-based thermometry and pH-responsive drug delivery using NaYF<sub>4</sub>:Yb,Er@SiO<sub>2</sub>-folic acid conjugates.

Journal of materials chemistry. B·2026
Same author

Azothiophene-based molecular switches: influence of substituent position and solvent environment on photophysical behavior.

Physical chemistry chemical physics : PCCP·2025
Same author

Calcium carbonate in drug delivery: functional carrier design, applications, and data-driven perspectives.

Expert opinion on drug delivery·2025
Same author

Encapsulation Strategy Matters: Pre- and Post-Loading of Macromolecules into Surface-Supported Microgels Formed via Vaterite Templates.

ACS materials Au·2025

Related Experiment Video

Updated: Aug 19, 2025

Encapsulation and Permeability Characteristics of Plasma Polymerized Hollow Particles
09:27

Encapsulation and Permeability Characteristics of Plasma Polymerized Hollow Particles

Published on: August 16, 2012

10.8K

Surface Modification with Particles Coated or Made of Polymer Multilayers.

Konstantinos T Kotoulas1, Jack Campbell1,2, Andre G Skirtach3

  • 1School of Science and Technology, Nottingham Trent University, Clifton Lane, Nottingham NG11 8NS, UK.

Pharmaceutics
|November 26, 2022
PubMed
Summary

This review explores how Layer-by-Layer (LbL) assembled particles attach to surfaces. It identifies key forces like Coulombic and capillary interactions, crucial for surface patterning and material modification.

Keywords:
coatingsimmobilizationlayer-by-layerpolyelectrolyte multilayers

More Related Videos

Author Spotlight: Exploring Self-Assembled MOF-Polymer Composites
06:48

Author Spotlight: Exploring Self-Assembled MOF-Polymer Composites

Published on: June 14, 2024

1.8K
Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers
10:09

Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers

Published on: June 30, 2018

8.4K

Related Experiment Videos

Last Updated: Aug 19, 2025

Encapsulation and Permeability Characteristics of Plasma Polymerized Hollow Particles
09:27

Encapsulation and Permeability Characteristics of Plasma Polymerized Hollow Particles

Published on: August 16, 2012

10.8K
Author Spotlight: Exploring Self-Assembled MOF-Polymer Composites
06:48

Author Spotlight: Exploring Self-Assembled MOF-Polymer Composites

Published on: June 14, 2024

1.8K
Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers
10:09

Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers

Published on: June 30, 2018

8.4K

Area of Science:

  • Materials Science
  • Surface Chemistry
  • Nanotechnology

Background:

  • Layer-by-Layer (LbL) assembly creates functional particles with diverse applications.
  • Existing literature lacks detailed understanding of LbL-assembled particle immobilization on surfaces.
  • Increased research highlights the need to clarify immobilization mechanisms.

Purpose of the Study:

  • To review and evaluate existing examples of immobilized LbL-assembled particles.
  • To identify and analyze the forces and factors influencing particle immobilization.
  • To propose a fundamental theory for LbL particle immobilization pathways.

Main Methods:

  • Literature review of studies involving immobilized LbL-assembled particles.
  • Analysis of forces (Coulombic, capillary, adhesive, hydrogen bonding, van der Waals, hydrophobic) influencing immobilization.
  • Examination of factors affecting immobilization, including particle morphology and surface charge.

Main Results:

  • Coulombic, capillary, and adhesive forces are predominant in LbL particle immobilization.
  • Particle morphology and surface charge significantly influence immobilization.
  • Immobilization can occur via physical (non-covalent) or chemical (covalent) bonds, with covalent bonds providing stronger adhesion.

Conclusions:

  • A theoretical framework for LbL particle immobilization pathways is proposed.
  • Understanding immobilization is key for surface patterning and modifying solid surfaces.
  • This review provides a foundation for future research in surface modification with polymer-based structures.