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Evaluation of Preprocessing Methods on Independent Medical Hyperspectral Databases to Improve Analysis.

Beatriz Martinez-Vega1, Mariia Tkachenko2,3, Marianne Matkabi2,4

  • 1Research Institute for Applied Microelectronics (IUMA), University of Las Palmas de Gran Canaria, 35017 Las Palmas de Gran Canaria, Spain.

Sensors (Basel, Switzerland)
|November 26, 2022
PubMed
Summary
This summary is machine-generated.

Preprocessing hyperspectral imaging (HSI) data is crucial for accurate cancer detection. Min-Max scaling emerged as the most effective technique across colorectal, esophagogastric, and brain cancer datasets, outperforming other methods.

Keywords:
brain cancercolon cancerdeep learningesophagogastric cancerhyperspectral imagingmachine learningmedian filtermin-max scalingstandard normal variate normalization

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Area of Science:

  • Medical imaging
  • Computational pathology
  • Cancer diagnostics

Background:

  • Cancer remains a leading global cause of mortality, necessitating advancements in early and accurate detection.
  • Hyperspectral Imaging (HSI) combined with artificial intelligence (AI) shows promise for cancer detection.
  • Standardized preprocessing methods for medical HSI data are lacking, hindering algorithm performance.

Purpose of the Study:

  • To evaluate and compare various preprocessing techniques for medical HSI data.
  • To determine the optimal preprocessing strategy for enhancing tumor detection across different cancer types.
  • To assess the impact of preprocessing on AI-based pixel-wise classification of HSI data.

Main Methods:

  • Evaluated combinations of spatial/spectral smoothing, Min-Max scaling, Standard Normal Variate (SNV) normalization, and median spatial smoothing.
  • Utilized two machine learning and deep learning models for pixel-wise classification.
  • Tested preprocessing methods on HSI datasets for colorectal, esophagogastric, and brain cancers.

Main Results:

  • Preprocessing significantly impacts tumor identification performance.
  • Median Filter preprocessing yielded slightly better results for colorectal tumors (AUC 0.94).
  • Min-Max scaling preprocessing achieved higher accuracy for esophagogastric (AUC 0.93) and brain tumors (AUC 0.92).

Conclusions:

  • Min-Max scaling is identified as the most relevant and robust preprocessing technique for HSI-based cancer detection across diverse datasets and instrumentation.
  • Median Filter can smooth critical spectral features, leading to performance variability.
  • Standardized preprocessing is essential for reliable AI-driven HSI cancer diagnostics.