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Related Experiment Video

Updated: Aug 19, 2025

Development of a Nose-only Inhalation Toxicity Test Chamber That Provides Four Exposure Concentrations of Nano-sized Particles

Development of a Nose-only Inhalation Toxicity Test Chamber That Provides Four Exposure Concentrations of Nano-sized Particles

Published on: March 18, 2019

Aerosol containment device design considerations and performance evaluation metrics.

Rachael M Jones¹, Niles Andrus², Thomas Dominguez²

¹Department of Family and Preventive Medicine, Spencer Fox Eccles School of Medicine, University of Utah, United States of America; Department of Environmental Health Sciences, Fielding School of Public Health, University of California, Los Angeles, United States of America.

The American Journal of Emergency Medicine

|November 26, 2022

Summary

Aerosol containment devices (ACDs) capture infectious respiratory aerosols. This review found few studies evaluated their effectiveness, user experience, or procedure impact, highlighting a need for standardized performance criteria.

Keywords:

Aerosol box COVID−19 Engineering controls Respiratory aerosols

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Published on: September 16, 2016

Area of Science:

Medical Devices
Infectious Disease Control
Respiratory Aerosols

Background:

Aerosol containment devices (ACDs) were developed during the COVID-19 pandemic to capture infectious respiratory aerosols at the source.
Previous reviews noted limited evidence of ACD effectiveness but lacked clear evaluation standards.
This study aimed to define design criteria by examining ACD design characteristics and their evaluation methods.

Approach:

A comprehensive scoping review was conducted following PRISMA guidelines.
Data extraction focused on study details, intended use, device design, and evaluation metrics.
Fifty-four relevant articles were included in the analysis.

Key Points:

Most evaluations (61%) focused on aerosol containment, with limited assessment of provider (9%) or patient (6%) experience, or procedure impact (15%).
Few studies established a priori performance criteria or benchmarked against external guidelines.
Studies assessing provider experience and procedure impact primarily focused on intubation.

Conclusions:

ACDs should achieve ≥90% respirable aerosol reduction for healthcare worker (HCP) protection, matching N95 respirator performance.
Devices must not negatively impact biomechanics or user comfort to ensure procedural success.
Integrating ACDs into practice requires robust studies on aerosol containment and user experience, utilizing standardized assessment tools.