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Updated: Aug 19, 2025

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
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[Functional assessment of serial coronary lesions and diffuse coronary disease]

Gábor Fülöp1, Bettina Csanádi1, Dávid Fülöp1

  • 11 Gottsegen György Országos Kardiovaszkuláris Intézet Budapest, Haller u. 29., 1096 Magyarország.

Orvosi Hetilap
|November 27, 2022
PubMed

Insights

Functional assessment during coronary angiography helps identify ischemia-causing lesions. New methods like pullback pressure gradient and instantaneous wave-free ratio improve treatment decisions for coronary artery disease.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Diagnostic Imaging

Context:

  • Traditional coronary angiography relies on anatomical data, often insufficient for determining ischemia severity.
  • Non-invasive functional tests may lack sensitivity and specificity for guiding treatment decisions.
  • Invasive functional tests have demonstrated clinical benefits in managing coronary artery disease.

Purpose:

  • To highlight the increasing role and clinical utility of functional assessment in diagnostic coronary angiography.
  • To discuss limitations of traditional anatomical assessment and the need for functional evaluation.
  • To introduce novel invasive functional assessment methods for coronary lesions.

Summary:

  • Functional assessment during coronary angiography provides crucial information on ischemia, complementing anatomical data.
  • Studies confirm the clinical benefit of invasive functional tests, correlating ischemia severity with prognosis.
  • Emerging techniques like pullback pressure gradient and instantaneous wave-free ratio enhance lesion assessment, especially for diffuse disease.

Impact:

  • Enables precise identification of ischemia-causing lesions for targeted revascularization.
  • Facilitates optimization of medical therapy when revascularization is not feasible.
  • Improves patient outcomes by guiding revascularization strategies and medical management in coronary artery disease.

Keywords:
percutan coronariaintervenciópercutaneous coronary intervention

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