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Updated: Aug 19, 2025

A Data-Driven Approach to Quantifying Immune States in Sepsis
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[Sepsis during pregnancy: Key points in 2022].

S Herbel1, F Uhel2, J Sibiude3

  • 1Département de maladies infectieuses et tropicales, hôpital Cochin, AP-HP, 27, rue du Faubourg Saint-Jacques, 75014 Paris, France; Médecine intensive réanimation, DMU ESPRIT, hôpital Louis-Mourier, AP-HP, 92700 Colombes, France.

Gynecologie, Obstetrique, Fertilite & Senologie
|November 27, 2022
PubMed
Summary
This summary is machine-generated.

Diagnosing and treating sepsis during pregnancy is complex due to physiological changes. This review synthesizes current knowledge on maternal sepsis, highlighting diagnostic challenges and treatment gaps to improve outcomes.

Keywords:
GrossesseInfectionInfection maternellePost-partumPost-partum periodPregnancyPuerperal infectionSepsis

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Area of Science:

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Critical Care Medicine

Context:

  • Pregnancy involves significant physiological alterations, complicating sepsis recognition.
  • Maternal sepsis diagnosis is challenging, risking delayed treatment and adverse outcomes.
  • Early and accurate diagnosis is crucial for effective sepsis management in pregnancy.

Purpose:

  • To review current diagnostic strategies for maternal sepsis.
  • To outline established treatment protocols for sepsis in pregnant patients.
  • To identify and highlight existing knowledge gaps in the field of maternal sepsis.

Summary:

  • Sepsis diagnosis in pregnancy is complicated by unique physiological changes.
  • Delayed treatment initiation due to diagnostic challenges leads to poorer maternal and fetal outcomes.
  • This review synthesizes current understanding and points to areas needing further research in maternal sepsis.

Impact:

  • Aims to improve the timely diagnosis and treatment of sepsis in pregnant individuals.
  • Highlights critical areas for future research to enhance maternal and fetal health outcomes.
  • Provides a foundation for evidence-based guidelines in managing maternal sepsis.